Evidence map›Paper›PMID 27901184›Full record

ArticleArchives of endocrinology and metabolism

Evaluation of salivary oxidative parameters in overweight and obese young adults.

Eduardo Ottobelli Chielle, Jeferson Noslen Casarin

Abstract read
In one paragraph

Article in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  3. Observational
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  8. Novel impacts of saliva with regard to oral health.The Journal of prosthetic dentistry · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eduardo Ottobelli ChielleDepartamento de Ciências da Saúde, Laboratório de Bioquímica Clínica, Universidade do Oeste de Santa Catarina (Unoesc), São Miguel do Oeste, SC, Brasil.
Jeferson Noslen CasarinDepartamento de Ciências da Saúde, Laboratório de Bioquímica Clínica, Universidade do Oeste de Santa Catarina (Unoesc), São Miguel do Oeste, SC, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is characterized by a deposition of abnormal or excessive fat in adipose tissue, and is linked with a risk of damage to several metabolic and pathological processes associated with oxidative stress. To date, salivary oxidative biomarkers have been minimally explored in obese individuals. Thus, the aim of this study was to assess the concentrations of salivary oxidative biomarkers (ferric-reducing antioxidant power, uric acid, sulfhydryl groups) and lipid peroxidation in obese and overweight young subjects. MATERIALS AND

methodsLevels of lipid peroxidation, ferric-reducing antioxidant power, uric acid, and SH groups were determined in the saliva and serum of 149 young adults, including 54 normal weight, 27 overweight, and 68 obese individuals. Anthropometric measurements were also evaluated.

resultsSalivary levels of ferric-reducing antioxidant power, sulfhydryl groups, and lipid peroxidation, as well as serum levels of ferric-reducing antioxidant power, uric acid, and lipid peroxidation were higher in obese patients when compared with individuals with normal weight. There were correlations between salivary and serum ferric-reducing antioxidant power and salivary and serum uric acid in the obese and normal-weight groups.

conclusionsOur results indicate that the increase in salivary levels of ferric-reducing antioxidant power, sulfhydryl groups, and lipid peroxidation, and serum levels of ferric-reducing antioxidant power, uric acid, and lipid peroxidation could be related to the regulation of various processes in the adipose tissue. These findings may hold promise in identifying new oxidative markers to assist in diagnosing and monitoring overweight and obese patients.

Indexed as

AdultAnthropometryAntioxidantsBiomarkersCase-Control StudiesFemaleHumansLipid PeroxidationMaleObesityOverweightOxidation-ReductionOxidative StressReactive Oxygen SpeciesReference ValuesSalivaAntioxidantsBiomarkersReactive Oxygen SpeciesSulfhydryl CompoundsThiobarbituric Acid Reactive SubstancesUric Acid

Identifiers

PMID27901184
PMCPMC10118870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.