ReviewEuropean journal of clinical nutrition2017
From the past to future: from energy expenditure to energy intake to energy expenditure.
Review in European journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Adipocyte Size, Overweight, and Insulin Resistance in Type 2 Diabetes Mellitus and the Impact of Weight Loss: A Systematic Review.Nutrients · 2026Pooled it
- Trial
- Post-operative Metabolic Adaptation and its Influence on Long-Term Recurrent Weight Gain After Metabolic and Bariatric Surgery.Obesity surgery · 2026Article
- From past to future: a review of methods for assessing physical activity energy expenditure.Journal of health, population, and nutrition · 2025Article
- Using Respiratory Gas Analyzers to Determine Resting Metabolic Rate in Adults: A Systematic Review of Validity Studies.Sports (Basel, Switzerland) · 2025Review
- Article
- Resting energy expenditure depends on energy intake during weight loss in people with obesity: a retrospective cohort study.Archives of endocrinology and metabolism · 2023Article
- Resting energy expenditure of a diverse group of South African men and women.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2022Article
- Food addiction and weight in students with high academic performance.Public health nutrition · 2021Article
- Resting Energy Expenditure and Related Factors in 6- to 9-Year-Old Southern African Children of Diverse Population Groups.Nutrients · 2021Article
- Resting metabolic rate and its adjustments as predictors of risk protein-energy wasting in hemodialysis patients.Bioscience reports · 2021Article
- Discovery and preclinical efficacy of HSG4112, a synthetic structural analog of glabridin, for the treatment of obesity.International journal of obesity (2005) · 2021Article
- Effects of a 3-Week In-Hospital Multidisciplinary Body Weight Reduction Program in Obese Females: Is Measured Resting Energy Expenditure Essential for Tailoring Adequately the Amount of Energy Intake?Frontiers in nutrition · 2021Article
- Associations of physical activity at work and household income with obesity: a cross-sectional study among rural adults in Korea.Epidemiology and health · 2021Article
- In utero nutritional stress as a cause of obesity: Altered relationship between body fat, leptin levels and caloric intake in offspring into adulthood.Life sciences · 2020Article
- Reconceptualizing anorexia nervosa.Psychiatry and clinical neurosciences · 2019Review
- SES-of-Origin and BMI in Youth: Comparing Germany and Minnesota.Behavior genetics · 2019Article
- Recent advances in understanding body weight homeostasis in humans.F1000Research · 2018Review
- Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas.Cellular and molecular life sciences : CMLS · 2017Review
- Prevalence of overweight and obesity among police officers in Riyadh City and risk factors for cardiovascular disease.Lipids in health and disease · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although most recent research on energy balance focusses on energy intake (EI) there is still need to think about both sides of the energy balance. Current research on energy expenditure (EE) relates to metabolic adaptation to negative energy balance, mitochondrial metabolism associated with aging, obesity and type 2 diabetes mellitus, the role of EE in hunger and appetite control, non-shivering thermogenesis and brown adipose tissue activity, cellular bioenergetics as a target of obesity treatment and the evolutionary and ecological determinants of EE in humans and other primates. As far as regulation of energy balance is concerned there is recent evidence that EE rather than body weight is under tight control. Biologically, EE is maintained within a narrow physiological range. An EE-set point has been proposed as the width between the upper and lower boundaries of the individual EE range. Regulation of EE may fail in very obese patients with an EI above their upper boundary and after drastic weight loss when patients may go far below their lower EE boundary and thus are loosing control. In population studies, fat-free mass (FFM) and its composition (that is, the proportion of high to low metabolic rate organs) are major determinants of EE. It is tempting to speculate that tight biologic control of EE is related to brain energy need, which is preserved at the cost of peripheral metabolism. There is a moderate heritability of EE, which is independent of the heritability of FFM. In future, metabolic phenotyping should focus on the EE-FFM relationship rather than on EE-values alone.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.