ArticleNature communications2016
Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- A Support-Free Strategy to Synthesize Sequence-Defined Macromolecules Using Solvent-Resistant Nanofiltration.Precision chemistry · 2026Article
- Visible and near-infrared light-induced photoclick reactions.Nature reviews. Chemistry · 2024Review
- Revealing the Effect of Stereocontrol on Intermolecular Interactions between Abiotic, Sequence-Defined Polyurethanes and a Ligand.ACS biomaterials science & engineering · 2024Article
- Nondestructive Sequencing of Enantiopure Oligoesters by Nuclear Magnetic Resonance Spectroscopy.JACS Au · 2022Article
- Microspheres from light-a sustainable materials platform.Nature communications · 2022Article
- Molecular data storage with zero synthetic effort and simple read-out.Scientific reports · 2022Article
- Semiautomated synthesis of sequence-defined polymers for information storage.Science advances · 2022Article
- Nature-Inspired Circular-Economy Recycling for Proteins: Proof of Concept.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Light-Triggered Click Chemistry.Chemical reviews · 2021Review
- Photoclick Chemistry: A Bright Idea.Chemical reviews · 2021Review
- Wavelength-Gated Photochemical Synthesis of Phenalene Diimides.Angewandte Chemie (International ed. in English) · 2021Article
- Applications of Discrete Synthetic Macromolecules in Life and Materials Science: Recent and Future Trends.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers.ACS macro letters · 2021Article
- Reading mixtures of uniform sequence-defined macromolecules to increase data storage capacity.Communications chemistry · 2020Article
- Dual sequence definition increases the data storage capacity of sequence-defined macromolecules.Communications chemistry · 2020Article
- Encoding Information into Polyethylene Glycol Using an Alcohol-Isocyanate "Click" Reaction.International journal of molecular sciences · 2020Article
- High-Throughput Tertiary Amine Deoxygenated Photopolymerizations for Synthesizing Polymer Libraries.Macromolecules · 2019Article
- Photo-editable macromolecular information.Nature communications · 2019Article
- Binary tree-inspired digital dendrimer.Nature communications · 2019Article
- A versatile strategy for the synthesis of sequence-defined peptoids with side-chain and backbone diversityChemical science · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Designing artificial macromolecules with absolute sequence order represents a considerable challenge. Here we report an advanced light-induced avenue to monodisperse sequence-defined functional linear macromolecules up to decamers via a unique photochemical approach. The versatility of the synthetic strategy-combining sequential and modular concepts-enables the synthesis of perfect macromolecules varying in chemical constitution and topology. Specific functions are placed at arbitrary positions along the chain via the successive addition of monomer units and blocks, leading to a library of functional homopolymers, alternating copolymers and block copolymers. The in-depth characterization of each sequence-defined chain confirms the precision nature of the macromolecules. Decoding of the functional information contained in the molecular structure is achieved via tandem mass spectrometry without recourse to their synthetic history, showing that the sequence information can be read. We submit that the presented photochemical strategy is a viable and advanced concept for coding individual monomer units along a macromolecular chain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.