Evidence map›Paper›PMID 27900513›Full record

ArticleMolecular diversity2017

Synthesis and antimicrobial evaluation of ester-linked 1,4-disubstituted 1,2,3-triazoles with a furyl/thienyl moiety.

C P Kaushik, Raj Luxmi, Dharmendra Singh, Ashwani Kumar

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. GeneFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

C P KaushikDepartment of Chemistry, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India. kaushikcp@gmail.com.
Raj LuxmiDepartment of Chemistry, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India.
Dharmendra SinghCentre for Research & Development, IPCA Lab Ltd., Kandivali, Mumbai, Maharashtra, India.
Ashwani KumarDepartment of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India.
Guru Jambheshwar University of Science and Technology · INIpca Laboratories (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty ester-linked 1,4-disubstituted 1,2,3-triazoles having a furyl/thienyl moiety have been synthesized from heteroaryl prop-2-yn-1-yl carboxylate and aromatic azides via a Cu(I) catalyzed 1,3-dipolar cycloaddition. All the synthesized compounds were characterized by FTIR, [Formula: see text]H NMR, [Formula: see text]C NMR spectroscopy and HRMS. Synthesized triazoles were tested in vitro for antimicrobial evaluation against Gram-negative bacteria-Escherichia coli, Enterobacter aerogenes and Klebsiella pneumoniae; Gram-positive bacteria-Staphylococcus aureus and two fungal strains-Candida albicans and Aspergillus niger, reflecting moderate to good activity. The structure of compound 6f was also confirmed by X-ray crystallography (CCDC 1469326).

Indexed as

Anti-Infective AgentsAspergillus nigerCandida albicansCatalytic DomainChemistry Techniques, SyntheticDNA GyraseEstersFuransGram-Negative BacteriaMolecular Docking SimulationTriazolesAnti-Infective AgentsDNA GyraseEstersfuranFuransTriazolesAntibacterial activityAntifungal activityClick chemistryDisubstituted 1,2,3-triazolesSynthesis

Identifiers

PMID27900513
OpenAlexW2558046765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.