ArticleEuropean radiology2017
Subsequent haemorrhage in children with untreated brain arteriovenous malformation: Higher risk with unbalanced inflow and outflow angioarchitecture.
Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review.F1000Research · 2023Pooled it
- Grades of brain arteriovenous malformations and risk of hemorrhage and death.Annals of clinical and translational neurology · 2019Pooled it
- Pediatric Brain AVM: The Role of DSA During Surgery in Hybrid Operating Room.Advances and technical standards in neurosurgery · 2026Article
- Editorial: Cerebral and spinal vascular malformations: from bench to bedside.Frontiers in neurology · 2023Article
- Quantitative evaluation of the subsequent hemorrhage with arteriography-derived hemodynamic features in patients with untreated cerebral arteriovenous malformation.Frontiers in neurology · 2023Article
- Signal intensity ratio of draining vein on silent MR angiography as an indicator of high-flow arteriovenous shunt in brain arteriovenous malformation.European radiology · 2021Article
- Commentary on "Signal intensity ratio of draining vein on silent MR angiography as an indicator of high-flow arteriovenous shunt in brain arteriovenous malformation".European radiology · 2021Article
- Multimodal Assessment of Cerebral Autoregulation and Autonomic Function After Pediatric Cerebral Arteriovenous Malformation Rupture.Neurocritical care · 2021Article
- Comparison of Endovascular Embolization Plus Simultaneous Microsurgical Resection vs. Primary Microsurgical Resection for High-Grade Brain Arteriovenous Malformations.Frontiers in neurology · 2021Article
- Natural history of high-grade pediatric arteriovenous malformations: implications for management options.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Surgical strategies for management of pediatric arteriovenous malformation rupture: the role of initial decompressive craniectomy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Contemporary management of brain arteriovenous malformations in mainland China: a web-based nationwide questionnaire survey.Chinese neurosurgical journal · 2020Article
- RNA Sequencing Reveals the Activation of Wnt Signaling in Low Flow Rate Brain Arteriovenous Malformations.Journal of the American Heart Association · 2019Article
- Evaluation of Angioarchitectural Features of Unruptured Brain Arteriovenous Malformation by Susceptibility Weighted Imaging.World neurosurgery · 2018Article
- Pediatric brain arteriovenous malformation unfavorable hemorrhage risk: extrapolation to a morphologic model.Chinese neurosurgical journal · 2018Article
- Multimodality management and outcomes of brain arterio-venous malformations (AVMs) in children: personal experience and review of the literature, with specific emphasis on age at first AVM bleed.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Review
- Morbidity after Hemorrhage in Children with Untreated Brain Arteriovenous Malformation.Cerebrovascular diseases (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesChildren with brain arteriovenous malformations (bAVMs) are at risk of life-threatening haemorrhage in their early lives. Our aim was to analyse various angioarchitectural features of bAVM to predict the risk of subsequent haemorrhage during follow-up in children.
methodsWe identified all consecutive children admitted to our institution for bAVMs between July 2009 and September 2015. Children with at least 1 month of treatment-free follow-up after diagnosis were included in further analysis. Annual rates of AVM rupture as well as several potential risk factors for subsequent haemorrhage were analysed using Kaplan-Meier analyses and Cox proportional hazards regression models.
resultsWe identified 110 paediatric patients with a mean follow-up period of 2.1 years (range, 1 month-15.4 years). The average annual risk of haemorrhage from untreated AVMs was 4.3 % in children. No generalised venous ectasia in conjunction with fast arteriovenous shunt was predictive of subsequent haemorrhage (RR, 7.55; 95 % CI 1.96-29.06). The annual rupture risk was 11.1 % in bAVMs without generalised venous ectasia but with fast arteriovenous shunt.
conclusionsbAVM angiographic features suggesting unbalanced inflow and outflow might be helpful to identify children at higher risk for future haemorrhage. KEY POINTS: • Haemorrhage risk stratification is important for children with untreated brain AVM. • Angiographic features suggesting unbalanced inflow and outflow predict paediatric brain AVM haemorrhage. • Identifying AVMs with high rupture risk help patient selection and tailoring treatment.
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