ArticlePediatric cardiology2017
Intact Imaging of Human Heart Structure Using X-ray Phase-Contrast Tomography.
Article in Pediatric cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Evolution of hierarchical phase-contrast tomography on the European Synchrotron beamlines BM05 and BM18: a whole adult human brain imaging case study.Journal of synchrotron radiation · 2026Article
- Synchrotron-based X-ray 3D phase contrast imaging and analysis of transmural myocardial tissue from heart failure patients.Scientific reports · 2025Article
- Three-dimensional structure of entire hydrated murine hearts at histological resolution.Scientific reports · 2025Article
- High-Resolution Phase-Contrast Tomography on Human Collagenous Tissues: A Comprehensive Review.Tomography (Ann Arbor, Mich.) · 2023Review
- Advances in TEE-Centric Intraprocedural Multimodal Image Guidance for Congenital and Structural Heart Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Structural properties in ruptured mitral chordae tendineae measured by synchrotron-based X-ray phase computed tomography.Journal of synchrotron radiation · 2023Article
- Mechanism of sac expansion without evident endoleak analyzed with X ray phase-contrast tomography.JVS-vascular science · 2023Article
- Impact of intraventricular septal fiber orientation on cardiac electromechanical function.American journal of physiology. Heart and circulatory physiology · 2022Article
- A tomographic microscopy-compatible Langendorff system for the dynamic structural characterization of the cardiac cycle.Frontiers in cardiovascular medicine · 2022Article
- Article
- Quantitative X-ray phase contrast computed tomography with grating interferometry : Biomedical applications of quantitative X-ray grating-based phase contrast computed tomography.European journal of nuclear medicine and molecular imaging · 2021Review
- Comprehensive assessment of myocardial remodeling in ischemic heart disease by synchrotron propagation based X-ray phase contrast imaging.Scientific reports · 2021Article
- First in situ 3D visualization of the human cardiac conduction system and its transformation associated with heart contour and inclination.Scientific reports · 2021Article
- A Review of Ex Vivo X-ray Microfocus Computed Tomography-Based Characterization of the Cardiovascular System.International journal of molecular sciences · 2021Review
- Evaluation of Ductal Tissue in Coarctation of the Aorta Using X-Ray Phase-Contrast Tomography.Pediatric cardiology · 2021Article
- Cardiac multi-scale investigation of the right and left ventricleCardiovascular diagnosis and therapy · 2020Review
- Multi-scale X-ray phase-contrast tomography of murine heart tissue.Biomedical optics express · 2020Article
- Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT.Journal of medical imaging (Bellingham, Wash.) · 2020Article
- Synchrotron Radiation-based X-ray phase-contrast imaging of the aortic walls in acute aortic dissection.JVS-vascular science · 2020Article
- Comprehensive Analysis of Animal Models of Cardiovascular Disease using Multiscale X-Ray Phase Contrast Tomography.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural examination of human heart specimens at the microscopic level is a prerequisite for understanding congenital heart diseases. It is desirable not to destroy or alter the properties of such specimens because of their scarcity. However, many of the currently available imaging techniques either destroy the specimen through sectioning or alter the chemical and mechanical properties of the specimen through staining and contrast agent injection. As a result, subsequent studies may not be possible. X-ray phase-contrast tomography is an imaging modality for biological soft tissues that does not destroy or alter the properties of the specimen. The feasibility of X-ray phase-contrast tomography for the structural examination of heart specimens was tested using infantile and fetal heart specimens without congenital diseases. X-ray phase-contrast tomography was carried out at the SPring-8 synchrotron radiation facility using the Talbot grating interferometer at the bending magnet beamline BL20B2 to visualize the structure of five non-pretreated whole heart specimens obtained by autopsy. High-resolution, three-dimensional images were obtained for all specimens. The images clearly showed the myocardial structure, coronary vessels, and conduction bundle. X-ray phase-contrast tomography allows high-resolution, three-dimensional imaging of human heart specimens. Intact imaging using X-ray phase-contrast tomography can contribute to further structural investigation of heart specimens with congenital heart diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.