Evidence map›Paper›PMID 27900080›Full record

ArticleMolecular and clinical oncology2016

Effect of an immunomodulatory regimen for cancer prevention: A case report.

Wenbo Wang, Wei Wang, Bing Liu, Zhuoyao Suo, Lin Zhou, Guangxian Liu

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wenbo WangChinese Medicine Department, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing 100071, P.R. China.
Wei WangCancer Therapy Center, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing 100071, P.R. China.
Bing LiuCancer Therapy Center, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing 100071, P.R. China.
Zhuoyao SuoCancer Therapy Center, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing 100071, P.R. China.
Lin ZhouCancer Therapy Center, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing 100071, P.R. China.
Guangxian LiuCancer Therapy Center, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing 100071, P.R. China.
Academy of Military Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present case study, an immunomodulatory regimen for cancer prevention is reported. A patient with an abnormally high level of the tumor markers, carbohydrate antigen-724 (CA724), CA19-9 and carcinoembryonic antigen (CEA), although without any detectable tumor, was treated with an immunomodulatory therapy featuring an infusion of cytokine-induced autologous killer cells (CIKs) at the request of the patient. Following the therapy, the three tumor markers rapidly decreased to below the normal reference level, although there still were slight fluctuations within a narrow range frequently. The patient was monitored for 21 months to the present day and no abnormality was observed. The results indicated that this therapy may be applied as a novel strategy that is effective and reliable for cancer prevention. As there is no promising regimen for the prevention of malignancies to date, such a treatment may become a major cancer prophylactic regimen, particularly for patients who are at a high risk of cancer.

Indexed as

cancercellular immunitycytokinecytokine-induced autologous killer cellsimmunomodulation

Identifiers

PMID27900080
PMCPMC5103862
OpenAlexW2520026067

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.