Evidence map›Paper›PMID 27900036›Full record

ArticleOncology letters2016

Management of pediatric head and neck rhabdomyosarcoma: A case-series of 36 patients.

Joanna Radzikowska, Wojciech Kukwa, Andrzej Kukwa, Anna M Czarnecka, Maciej Kawecki, Fei Lian, Cezary Szczylik, Antoni Krzeski

Abstract read
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Rhabdomyosarcoma of the Middle Ear Case Report.Children (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Non-inferior efficacy of non-surgical treatment to surgical treatment in patients with nonmetastatic head and neck rhabdomyosarcoma: a SEER-based study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  9. Clinical-pathologic profile of head and neck rhabdomyosarcoma in children: a systematic review.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2023
    Review
  10. Paediatric head and neck malignant neoplasms: A brazilian retrospective study.Medicina oral, patologia oral y cirugia bucal · 2023
    Article
  11. Article
  12. Article
  13. [Clinical analysis of 35 cases of adult rhabdomyosarcoma of nasal cavity and sinuses].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Cervicofacial Rhabdomyosarcoma - Success of a Free Fibular Graft.Journal of Indian Association of Pediatric Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanna RadzikowskaDepartment of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw 00-739, Poland.
Wojciech KukwaDepartment of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw 00-739, Poland.
Andrzej KukwaDepartment of Otolaryngology and Head and Neck Disease, University of Varmia and Mazury, Olsztyn 10-082, Poland.
Anna M CzarneckaDepartment of Oncology and Molecular Oncology Laboratory, Military Institute of Medicine,Warsaw 04-141, Poland.
Maciej KaweckiDepartment of Oncology and Molecular Oncology Laboratory, Military Institute of Medicine,Warsaw 04-141, Poland.
Fei LianDepartment of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Cezary SzczylikDepartment of Oncology and Molecular Oncology Laboratory, Military Institute of Medicine,Warsaw 04-141, Poland.
Antoni KrzeskiDepartment of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw 00-739, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric population. In 35% of cases, RMS develops in the head and neck (H&N) region, and only combined therapy is recognized as a curative treatment. However, recent advances in skull base and reconstructive surgery, along with microsurgery and endoscopic surgery, have strengthened the role of surgery as an important part of RMS treatment. In the present study, 36 pediatric RMS cases (24 males and 12 females) were analyzed after surgical treatment. The average age at diagnosis was 7 years. In total, 67% of tumors were localized in the parameningeal region. Alveolar RMS was the most common histopathological type. A total of 16 patients were treated due to disease recurrence or a previous non-radical surgical procedure, while 19 cases had inductive chemotherapy and/or radiotherapy preceding surgical treatment due to locally advanced disease. In 1 case, only diagnostic biopsy was performed. It is recommended that the management of H&N RMS is interdisciplinary from the beginning. Extensive surgical dissection in the H&N region for RMS may result in severe cosmetic defects and functional impairment; thus, these risks should be considered during treatment planning, and the surgical approach should be based on the individual characteristics of each patient.

Indexed as

head and neck cancerneoplasmrhabdomyosarcomasarcomasurgery

Identifiers

PMID27900036
PMCPMC5104052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.