Evidence map›Paper›PMID 27899956›Full record

ArticleEcancermedicalscience2016

Innovations that reach the patient: early health technology assessment and improving the chances of coverage and implementation.

W H van Harten, V P Retèl

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

W H van HartenThe Netherlands Cancer Institute, PO Box 90203, 1006 BE Amsterdam, The Netherlands; University of Twente, Department of Healthcare Technology and Services Research, PO Box 217, 7500 AE Enschede, The Netherlands; Rijnstate Hospital, PO Box 9555, 6800 TA Arnhem, The Netherlands.
V P RetèlThe Netherlands Cancer Institute, PO Box 90203, 1006 BE Amsterdam, The Netherlands; University of Twente, Department of Healthcare Technology and Services Research, PO Box 217, 7500 AE Enschede, The Netherlands.
Rijnstate Hospital · NLThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With growing concerns for the sustainability of the financial burden that health care-and especially cancer services-poses on the national budgets, the role of health economic analyses in coverage decisions is likely to grow. One of the strategies for the biomedical research field-also in oncology research-to foster coverage and health system implementation, is to anticipate this new role and to involve health technology assessment techniques earlier in various stages of translational research. In this article, we elaborate on the early involvement of health technology assessment in translational research and the concept of Coverage with Evidence Development in The Netherlands Cancer Institute and give two case examples that are currently ongoing: (1) tumour infiltrating lymphocytes therapy for metastatic melanoma; and (2) high-dose chemotherapy for BRCA1-like subgroup in triple-negative breast cancer. We conclude with recommendations for institutional policy.

Indexed as

coverage with evidence developmenthealth technology assessmenthigh-dose chemotherapytumour infiltrating lymphocytes

Identifiers

PMID27899956
PMCPMC5102688
OpenAlexW2543442644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.