ArticleJournal of geriatric cardiology : JGC2016
Beta-blocker use and risk of symptomatic bradyarrhythmias: a hospital-based case-control study.
Article in Journal of geriatric cardiology : JGC, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Efficacy and safety of guanxinshutong capsule as adjunctive therapy for unstable angina: an integrated systematic review, meta-analysis, and network pharmacology study.Frontiers in cardiovascular medicine · 2026Review
- Efficacy and safety of guanxinshutong capsule combined with western medicine on stable angina pectoris: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Review
- Beta-Blocker-Related Atrioventricular Conduction Disorders-A Single Tertiary Referral Center Experience.Medicina (Kaunas, Lithuania) · 2022Article
- Long-term impact of β-blocker in elderly patients without myocardial infarction after percutaneous coronary intervention.ESC heart failure · 2022Article
- Electrocardiography findings in right ventricular apical pacing.Singapore medical journal · 2020Article
- Heart rate determines the beneficial effects of beta-blockers on cardiovascular outcomes in patients with heart failure and atrial fibrillation.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Beta-Blockers for Migraine Prevention: a Review Article.Current treatment options in neurology · 2019Review
- Management of Arrhythmias in Heart Failure.Journal of cardiovascular development and disease · 2017Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the risk factors of symptomatic bradyarrhythmias in relation to β-blockers use.
methodsA hospital-based case-control study [228 patients: 108 with symptomatic bradyarrhythmias (cases) and 120 controls] was conducted in Sultanah Aminah Hospital, Malaysia between January 2011 and January 2014.
resultsThe mean age was 61.1 ± 13.3 years with a majority of men (68.9%). Cases were likely than control to be older, hypertensive, lower body mass index and concomitant use of rate-controlling drugs (such as digoxin, verapamil, diltiazem, ivabradine or amiodarone). Significantly higher level of serum potassium, urea, creatinine and lower level of estimated glomerular filtration rate (eGFR) were observed among cases as compared to controls. On univariate analysis among patients on β-blockers, older age (crude OR: 1.07; 95% CI: 1.03-1.11,
conclusionOlder age was a significant predictor of symptomatic bradyarrhythmias in patients on β-blockers than those without β-blockers.
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Registered trials
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