ReviewFrontiers in pharmacology2016
Raynaud's Phenomenon: A Brief Review of the Underlying Mechanisms.
Review in Frontiers in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Raynaud Syndrome Associated with Medication for Attention-Deficit/Hyperactivity Disorder: A Systematic Review.CNS drugs · 2025Pooled it
- The use of acupuncture in patients with Raynaud's syndrome: a systematic review and meta-analysis of randomized controlled trials.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2023Pooled it
- Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial.Biomolecules · 2019Trial
- Cold responses and hormonal echoes: a comprehensive view of Raynaud's vascular dysfunction.Inflammopharmacology · 2025Review
- Association Between Risk of Relapse and Type of Surgical Procedure for Raynaud's Disease.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Inhibiting Intracellular αInternational journal of molecular sciences · 2023Article
- Article
- Solvent-Induced Raynaud's Phenomenon.Cureus · 2023Article
- Comparison of the efficacy and safety of oligomeric proanthocyanidins and nifedipine in patients with primary Raynaud's phenomenon: An open-label, randomized, prospective pilot study.Archives of rheumatology · 2023Article
- Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank.Nature communications · 2023Article
- Diurnal rhythmicity of wearable device-measured wrist temperature predicts future disease incidence in the UK Biobank.Research square · 2023Article
- Worsening of Primary Raynaud's Phenomenon During Episodes of Pyrexia and Rigors in SARS-CoV-2 Infection.Cureus · 2023Article
- Animal Models of Systemic Sclerosis: Using Nailfold Capillaroscopy as a Potential Tool to Evaluate Microcirculation and Microangiopathy: A Narrative Review.Life (Basel, Switzerland) · 2022Review
- G protein estrogen receptor as a potential therapeutic target in Raynaud's phenomenon.Frontiers in pharmacology · 2022Article
- Review
- Design of Electro-Thermal Glove with Sensor Function for Raynaud's Phenomenon Patients.Materials (Basel, Switzerland) · 2021Article
- EPAC in Vascular Smooth Muscle Cells.International journal of molecular sciences · 2020Review
- The Mitochondria: A Target of Polyphenols in the Treatment of Diabetic Cardiomyopathy.International journal of molecular sciences · 2020Review
- Injection Techniques for Common Chronic Pain Conditions of the Hand: A Comprehensive Review.Pain and therapy · 2020Review
- Estrogen and Bisphenol A in Hypertension.Current hypertension reports · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Raynaud's phenomenon (RP) is characterized by exaggerated cold-induced vasoconstriction. This augmented vasoconstriction occurs by virtue of a reflex response to cooling via the sympathetic nervous system as well as by local activation of α
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.