Evidence map›Paper›PMID 27899692›Full record

ArticleSLAS discovery : advancing life sciences R & D2017

Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform.

Ioannis K Moutsatsos, Imtiaz Hossain, Claudia Agarinis, Fred Harbinski, Yann Abraham, Luc Dobler, Xian Zhang, Christopher J Wilson, Jeremy L Jenkins, Nicholas Holway and 2 more

Abstract read
In one paragraph

Article in SLAS discovery : advancing life sciences R & D, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ioannis K Moutsatsos1 Developmental and Molecular Pathways, NIBR, Cambridge, MA, USA.
Imtiaz Hossain2 Centre for Proteomic Chemistry, NIBR, Postfach, Basel, Switzerland.
Claudia Agarinis3 Developmental and Molecular Pathways, NIBR, Postfach, Basel, Switzerland.
Fred Harbinski4 Editas Medicine, Cambridge, MA, USA.
Yann Abraham5 The Janssen Pharmaceutical Companies of Johnson & Johnson, Beerse, Vlaanderen, Belgium.
Luc Dobler6 République et Canton du Jura, Switzerland.
Xian Zhang2 Centre for Proteomic Chemistry, NIBR, Postfach, Basel, Switzerland.
Christopher J Wilson4 Editas Medicine, Cambridge, MA, USA.
Jeremy L Jenkins1 Developmental and Molecular Pathways, NIBR, Cambridge, MA, USA.
Nicholas Holway7 Scientific Computing, NIBR Informatics, Novartis, Postfach, Basel, Switzerland.
John Tallarico1 Developmental and Molecular Pathways, NIBR, Cambridge, MA, USA.
Christian N Parker3 Developmental and Molecular Pathways, NIBR, Postfach, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such applications is challenging but highly valuable. Scientific data integration and pipelining facilitate standardized data processing, collaboration, and reuse of best practices. We describe how Jenkins-CI, an "off-the-shelf," open-source, continuous integration system, is used to build pipelines for processing images and associated data from high-content screening (HCS). Jenkins-CI provides numerous plugins for standard compute tasks, and its design allows the quick integration of external scientific applications. Using Jenkins-CI, we integrated CellProfiler, an open-source image-processing platform, with various HCS utilities and a high-performance Linux cluster. The platform is web-accessible, facilitates access and sharing of high-performance compute resources, and automates previously cumbersome data and image-processing tasks. Imaging pipelines developed using the desktop CellProfiler client can be managed and shared through a centralized Jenkins-CI repository. Pipelines and managed data are annotated to facilitate collaboration and reuse. Limitations with Jenkins-CI (primarily around the user interface) were addressed through the selection of helper plugins from the Jenkins-CI community.

Indexed as

AlgorithmsUser-Computer InterfaceAnimalsCell LineGene Expression RegulationHumansImage Processing, Computer-AssistedInternetMolecular ImagingPhosphoproteinsRNA, Small InterferingWorkflowPhosphoproteinsRNA, Small InterferingCellProfilercontinuous integrationhigh-content screeninghigh-performance computing

Identifiers

PMID27899692
PMCPMC5322829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.