Evidence map›Paper›PMID 27899660›Full record

ArticleNucleic acids research2017

CEBS: a comprehensive annotated database of toxicological data.

Isabel A Lea, Hui Gong, Anand Paleja, Asif Rashid, Jennifer Fostel

Abstract read
In one paragraph

Article in Nucleic acids research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Unlocking the potential of AI: Machine learning and deep learning models for predicting carcinogenicity of chemicals.Journal of environmental science and health. Part C, Toxicology and carcinogenesis · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Machine Learning and Artificial Intelligence in Toxicological Sciences.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Emerging Bioinformatics Methods and Resources in Drug Toxicology.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  18. In Silico Methods for Chromosome Damage.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  19. Essential oil fromBulletin of the National Research Centre · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isabel A LeaASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA Isabel.lea@nih.gov.
Hui GongASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA.
Anand PalejaASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA.
Asif RashidASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA.
Jennifer FostelDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, PO Box 12233, Research Triangle Park, NC 27709, USA fostel@niehs.nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Chemical Effects in Biological Systems database (CEBS) is a comprehensive and unique toxicology resource that compiles individual and summary animal data from the National Toxicology Program (NTP) testing program and other depositors into a single electronic repository. CEBS has undergone significant updates in recent years and currently contains over 11 000 test articles (exposure agents) and over 8000 studies including all available NTP carcinogenicity, short-term toxicity and genetic toxicity studies. Study data provided to CEBS are manually curated, accessioned and subject to quality assurance review prior to release to ensure high quality. The CEBS database has two main components: data collection and data delivery. To accommodate the breadth of data produced by NTP, the CEBS data collection component is an integrated relational design that allows the flexibility to capture any type of electronic data (to date). The data delivery component of the database comprises a series of dedicated user interface tables containing pre-processed data that support each component of the user interface. The user interface has been updated to include a series of nine Guided Search tools that allow access to NTP summary and conclusion data and larger non-NTP datasets. The CEBS database can be accessed online at http://www.niehs.nih.gov/research/resources/databases/cebs/.

Indexed as

Databases, FactualSearch EngineToxicologyDatabases, Nucleic AcidHumansToxicogeneticsUser-Computer InterfaceWeb Browser

Identifiers

PMID27899660
PMCPMC5210559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.