Evidence map›Paper›PMID 27899528›Full record

ArticleEuropean journal of preventive cardiology2017

Relationship between outdoor temperature and cardiovascular disease risk factors in older people.

Claudio Sartini, Sarah Je Barry, Peter H Whincup, S Goya Wannamethee, Gordon DO Lowe, Barbara J Jefferis, Lucy Lennon, Paul Welsh, Ian Ford, Naveed Sattar and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in European journal of preventive cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Claudio Sartini1 Department of Primary Care and Population Health, University College London, UK.
Sarah Je Barry2 Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences. Robertson Centre for Biostatistics, University of Glasgow, UK.
Peter H Whincup3 Population Health Research Institute, St George's University of London, UK.
S Goya Wannamethee1 Department of Primary Care and Population Health, University College London, UK.
Gordon DO Lowe4 Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.
Barbara J Jefferis1 Department of Primary Care and Population Health, University College London, UK.
Lucy Lennon1 Department of Primary Care and Population Health, University College London, UK.
Paul Welsh2 Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences. Robertson Centre for Biostatistics, University of Glasgow, UK.
Ian Ford2 Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences. Robertson Centre for Biostatistics, University of Glasgow, UK.
Naveed Sattar4 Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.
Richard W Morris5 School of Social and Community Medicine, University of Bristol, UK.
University of Glasgow · GBUniversity College London · GBSt George's, University of London · GBUniversity of Bristol · GB

Funding

British Heart Foundation PG/09/024/26857British Heart Foundation PG/13/41/30304British Heart Foundation RG/08/013/25942British Heart Foundation RG/13/16/30528
6 · The paper itself

Abstract

Background Previous studies demonstrated that lower outdoor temperatures increase the levels of established cardiovascular disease risk factors, such as blood pressure and lipids. Whether or not low temperatures increase novel cardiovascular disease risk factors levels is not well studied. The aim was to investigate associations of outdoor temperature with a comprehensive range of established and novel cardiovascular disease risk factors in two large Northern European studies of older adults, in whom cardiovascular disease risk is increased. Design and methods Data came from the British Regional Heart Study (4252 men aged 60-79 years) and the Prospective Study of Pravastatin in the Elderly at Risk (5804 men and women aged 70-82 years). Associations between outdoor temperature and cardiovascular disease risk factors were quantified in each study and then pooled using a random effects model. Results With a 5℃ lower mean temperature, total cholesterol was 0.04 mmol/l (95% confidence interval (CI) 0.02-0.07) higher, low density lipoprotein cholesterol was 0.02 mmol/l (95% CI 0.01-0.05) higher and SBP was 1.12 mm Hg (95% CI 0.60-1.64) higher. Among novel cardiovascular disease risk factors, C-reactive protein was 3.3% (95% CI 1.0-5.6%) higher, interleukin-6 was 2.7% (95% CI 1.1-4.3%) higher, and vitamin D was 11.2% (95% CI 1.0-20.4%) lower. Conclusions Lower outdoor temperature was associated with adverse effects on cholesterol, blood pressure, circulating inflammatory markers, and vitamin D in two older populations. Public health approaches to protect the elderly against low temperatures could help in reducing the levels of several cardiovascular disease risk factors.

Indexed as

TemperatureAgedAged, 80 and overAge FactorsBiomarkersCardiovascular DiseasesCohort StudiesEuropeFemaleHealth BehaviorHumansMaleMiddle AgedRisk FactorsBiomarkersBiomarkerscardiovascular disease risk factorsolder adultsoutdoor temperature

Identifiers

PMID27899528
PMCPMC5301906
OpenAlexW2559379480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.