Evidence map›Paper›PMID 27899095›Full record

ArticleBMC complementary and alternative medicine2016

Effects of the Ayurved Siriraj Wattana recipe on functional and phenotypic characterization of cytokine-induced killer cells and dendritic cells in vitro.

Adisak Wongkajornsilp, Nuntarak Numchaisermsuk, Khanit Sa-Ngiamsuntorn, Pravit Akarasereenont, Valla Wamanuttajinda, Kanda Kasetsinsombat, Sunisa Duangsa-Ard, Tawee Laohapan, Kittipong Maneechotesuwan

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Adisak WongkajornsilpDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Nuntarak NumchaisermsukDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Khanit Sa-NgiamsuntornDepartment of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand.
Pravit AkarasereenontDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Valla WamanuttajindaDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Kanda KasetsinsombatDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Sunisa Duangsa-ArdDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Tawee LaohapanCenter of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Kittipong ManeechotesuwanDepartment of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. kittipong.man@mahidol.ac.th.ORCID http://orcid.org/0000-0001-5940-7436
Siriraj Hospital · THMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAyurved Siriraj Wattana recipe (AVS073), has been prescribed as tonic, to increase appetite, and for pain relief. It also exhibits antioxidant, anti-inflammatory, immunomodulating and anti-cancer activities. However, the immunomodulatory effects on antigen-presenting cells and effector T cells remained elusive. We thus aimed to study the effects of AVS073 on differentiation, maturation, functions and proportions of CIK cells and monocyte-derived DCs.

methodsCIK cells and monocyte-derived DCs were treated with AVS073, followed by the assessment of T-helper (Th) phenotypes using real-time RT-PCR and flow cytometry.

resultsAVS073 promoted Th1 phenotype in CD3

conclusionsAVS073 upregulated Th1 and Th17, but downregulated Th2 and Treg phenotypes within CD3

Indexed as

CD3 ComplexCD56 AntigenCell ProliferationCells, CulturedCell SurvivalCytokine-Induced Killer CellsCytokinesDendritic CellsHumansImmunophenotypingPlant PreparationsPlants, MedicinalThailandT-Lymphocyte SubsetsCD3 ComplexCD56 AntigenCytokinesPlant PreparationsCIK cellsCytotoxicityDendritic cellsImmunomodulationLymphocytesTraditional medicine Asia

Identifiers

PMID27899095
PMCPMC5129228
OpenAlexW2559492605

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.