Evidence map›Paper›PMID 27899003›Full record

ArticleArthritis care & research2017

Dietary Fiber Intake in Relation to Knee Pain Trajectory.

Zhaoli Dai, Na Lu, Jingbo Niu, David T Felson, Yuqing Zhang

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Arthritis care & research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. The effects of dietary patterns and food groups on symptomatic osteoarthritis: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2023
    Pooled it
  2. Pooled it
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  7. Gut microbiota-mediated pain sensitization: mechanisms and therapeutic implications.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Review
  8. Article
  9. Article
  10. Dietary fiber may benefit chondrocyte activity maintenance.Frontiers in cellular and infection microbiology · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhaoli DaiBoston University School of Medicine, Boston, Massachusetts.
Na LuBoston University School of Medicine, Boston, Massachusetts.
Jingbo NiuBoston University School of Medicine, Boston, Massachusetts.
David T FelsonBoston University School of Medicine, Boston, Massachusetts.
Yuqing ZhangBoston University School of Medicine, Boston, Massachusetts.
Boston University · US

Funding

WORK DISABILITY-- PERSONS WITH RHEUMATOID ARTHRITISP60AR047785 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2016
$18.0M
DATA COORDINATING CENTER FOR THE OSTEOARTHRITIS INITIATIVEN01AR22258 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEVITT, MICHAEL · 2007 to 2011
$13.5M
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVEN01AR22259 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE · PI HOCHBERG, MARC C. · 2007 to 2011
$7.8M
Clinical Centers for the Osteoarthritis Initiative^Rhode IslandN01AR22262 · NIAMS · MEMORIAL HOSPITAL OF RHODE ISLAND · PI EATON, CHARLES B. · 2007 to 2010
$6.8M
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVEN01AR22261 · NIAMS · OHIO STATE UNIVERSITY RESEARCH FDN · PI JACKSON, REBECCA · 2007 to 2011
$6.2M
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVEN01AR22260 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2007 to 2010
$6.1M
Relation of Alignment and Other Risk Factors to Knee OAR01AR051568 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2006 to 2010
$2.5M
RHEUMATOLOGY TRAINING GRANTT32AR007598 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 1997 to 2018
$2.3M
CLINICAL CENTER FOR THE OSTEOARTHRITIS-264022262-264022262N01AR022262 · NIAMS · THE MEMORIAL HOSPITAL · PI ASSAF, ANNLOUISE R. · 2002 to 2006
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22261N01AR022261 · NIAMS · OHIO STATE UNIVERSITY RESEARCH · PI JACKSON, REBECCA · 2002 to 2006
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22260N01AR022260 · NIAMS · UNIVERSITY OF PITTSBURGH · PI KWOH, KENT · 2002 to 2006
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NEW PHARMACOLOGY ASPECTS RELATED TO CARBONIC ANHYDRASER01HL022258 · NHLBI · UNIVERSITY OF FLORIDA · PI MAREN, THOMAS H · 1985 to 1986
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NHLBI NIH HHS N01AR22258NIAMS NIH HHS N01AR22259NIAMS NIH HHS N01AR22260NIAMS NIH HHS N01AR22261NIAMS NIH HHS N01AR22262NIAMS NIH HHS P60 AR047785NIAMS NIH HHS R01 AR051568NIAMS NIH HHS T32 AR007598
6 · The paper itself

Abstract

objectiveDietary fiber may reduce knee pain, in part by lowering body weight and reducing inflammation. In this study, we assessed whether fiber intake was associated with patterns of knee pain development.

methodsIn a prospective, multicenter cohort of 4,796 men and women ages 45-79 years with or at risk of knee osteoarthritis, participants underwent annual followups for 8 years. Dietary fiber intake was estimated using a validated food frequency questionnaire at baseline. Group-based trajectory modeling was used to identify Western Ontario and McMaster Universities Osteoarthritis Index pain trajectories, which were assessed for associations with dietary fiber intake using polytomous regression models.

resultsOf the eligible participants (4,470 persons and 8,940 knees, mean ± SD age 61.3 ± 9.1 years, 58% women), 4.9% underwent knee replacement and were censored at the time of surgery. Four distinct knee pain patterns were identified: no pain (34.5%), mild pain (38.1%), moderate pain (21.2%), and severe pain (6.2%). Dietary total fiber was inversely related to membership in the moderate or severe pain groups (P ≤ 0.006 for trend for both). Subjects in the highest versus those in the lowest quartile of total fiber intake had a lower risk of belonging to the moderate pain pattern group (odds ratio [OR] 0.76 [95% confidence interval (95% CI) 0.61-0.93]) and severe pain pattern group (OR 0.56 [95% CI 0.41-0.78]). Similar results were found with grain fiber and these 2 pain pattern groups.

conclusionOur findings suggest that a high intake of dietary total or grain fiber, particularly the recommended daily fiber average intake of 25 gm per day, is associated with a lower risk of developing moderate or severe knee pain over time.

Indexed as

Knee JointAgedArthralgiaDietary FiberDiet SurveysFemaleFollow-Up StudiesHumansMaleMiddle AgedOdds RatioOsteoarthritis, KneePain MeasurementProspective StudiesRisk FactorsTime FactorsDietary Fiber

Identifiers

PMID27899003
PMCPMC5447491
OpenAlexW2559085940

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.