Evidence map›Paper›PMID 27898458›Full record

ArticleThe Clinical journal of pain2017

Smoking Status and Opioid-related Problems and Concerns Among Men and Women on Chronic Opioid Therapy.

Kelly C Young-Wolff, Daniella Klebaner, Constance Weisner, Michael Von Korff, Cynthia I Campbell

Open access · greenAbstract read
In one paragraph

Article in The Clinical journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kelly C Young-Wolff*Division of Research, Kaiser Permanente Northern California, Oakland †Department of Psychiatry, University of California, San Francisco, CA ‡Group Health Research Institute, Seattle, WA.
Daniella Klebaner
Constance Weisner
Michael Von Korff
Cynthia I Campbell
Kaiser Permanente · USUniversity of California, San Francisco · USKaiser Permanente Washington Health Research Institute · US

Funding

Long-term Opioid Management of Chronic Pain: Trends and RisksR01DA022557 · NIDA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2006 to 2009
$2.4M
NIDA NIH HHS R01 DA022557
6 · The paper itself

Abstract

objectivesSmokers on chronic opioid therapy (COT) for noncancer pain use prescription opioids at higher dosages and are at increased risk for opioid misuse and dependence relative to nonsmokers. The current study aims to assess whether smoking is associated with problems and concerns with COT from the perspective of the patient. MATERIALS AND

methodsIn a large sample (N=972) of adult patients prescribed opioids for chronic noncancer pain, we examined sex-specific associations between smoking status and patient perceptions of problems and concerns with COT using regression analyses, adjusting for covariates.

resultsThe sample self-identified as 27% current smokers, 44% former smokers, and 29% never smokers. Current smoking (vs. never smoking) was associated with increased odds of an opioid use disorder among males and females, and higher daily opioid dose among males only. Current and former smokers reported significantly fewer problems with opioids relative to never smokers, and this was driven primarily by lower endorsement of problems that are affected by the stimulant properties of nicotine (eg, difficulties thinking clearly, felt less alert or sleepy). DISCUSSION: This study contributes to an understanding of perceived problems and concerns with COT among current, former, and never smokers with chronic noncancer pain. Results suggest that current and former smokers may be a difficult population to target to decrease COT, given that they perceive fewer problems with prescription opioid use, despite higher odds of having an opioid use disorder (males and females) and greater opioid doses (males only).

Indexed as

AdultAgedAnalgesics, OpioidFemaleHumansMaleMiddle AgedMultivariate AnalysisOpioid-Related DisordersRegression AnalysisRisk FactorsSex FactorsSmokingYoung AdultAnalgesics, Opioid

Identifiers

PMID27898458
PMCPMC5446933
OpenAlexW2557639865

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.