Evidence map›Paper›PMID 27898172›Full record

ArticleJournal of the American Geriatrics Society2017

Association Between Hospital Readmission and Acute and Sustained Delays in Functional Recovery During 18 Months After Elective Surgery: The Successful Aging after Elective Surgery Study.

Margaret A Pisani, Asha Albuquerque, Edward R Marcantonio, Richard N Jones, Ray Yun Gou, Tamara G Fong, Eva M Schmitt, Douglas Tommet, Ilean I Isaza Aizpurua, David C Alsop and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Margaret A PisaniSchool of Medicine, Yale University, New Haven, Connecticut.
Asha AlbuquerqueSchool of Medicine, Yale University, New Haven, Connecticut.
Edward R MarcantonioHarvard Medical School, Boston, Massachusetts.
Richard N JonesDepartments of Psychiatry and Human Behavior, Brown University Warren Alpert Medical School, Providence, Rhode Island.ORCID 0000-0002-1049-218X
Ray Yun GouInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Tamara G FongInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Eva M SchmittInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Douglas TommetDepartments of Psychiatry and Human Behavior, Brown University Warren Alpert Medical School, Providence, Rhode Island.
Ilean I Isaza AizpuruaInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
David C AlsopHarvard Medical School, Boston, Massachusetts.
Sharon K InouyeInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Thomas G TravisonInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Beth Israel Deaconess Medical Center · USHebrew SeniorLife · USBrown University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2010 to 2022
$26.7M
READI-SET-GO: Researching Efficient Approaches to Delirium Identification - Sustaining Effective Translation to create Gero-friendly OrganizationsR01AG030618 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI DONNA Marie FICK, EDWARD R MARCANTONIO · 2008 to 2026
$7.9M
Mid-Career Mentoring Award for Patient-Oriented Research in AgingK24AG035075 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MARCANTONIO, EDWARD R · 2010 to 2021
$1.9M
K07 Leadership GrantK07AG041835 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2013 to 2017
$656k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K07 AG041835NIA NIH HHS K24 AG035075NIA NIH HHS P01 AG031720NIA NIH HHS R01 AG030618
6 · The paper itself

Abstract

objectivesTo examine the effect of hospital readmission on functional recovery after elective surgery in older adults.

designProspective cohort of individuals aged 70 and older undergoing elective surgery, enrolled from June 2010 to August 2013.

settingTwo academic medical centers.

participantsCommunity-dwelling older adults (N = 566; mean age ± standard deviation 77 ± 5) undergoing major elective surgery and expected to be admitted for at least 3 days. MEASUREMENTS: Readmission was assessed in multiple interviews with participants and family members over 18 months and validated against medical record review. Physical function was assessed according to ability to perform instrumental activities of daily living (IADLs) and activities of daily living (ADL), Medical Outcomes Study 12-item Short-Form Survey Physical Component Summary score, and a standardized functional composite.

resultsTwo hundred fifty-five (45%) participants experienced 503 readmissions. Readmissions were associated with delays in functional recovery in all measures of physical function. Having two or more readmissions over 18 months was associated with persistent and significantly greater risk of IADL dependence (relative risk (RR) = 1.8, 95% confidence interval (CI) = 1.5-2.3) and ADL dependence (RR = 3.3, 95% CI = 1.7-6.4). Degree of functional impairment increased progressively with number of readmissions. Readmissions within 2 months resulted in delayed functional recovery to baseline by 18 months, and readmissions between 12 and 18 months after surgery resulted in loss of functional recovery previously achieved.

conclusionReadmission after elective surgery may contribute to delays in functional recovery and persistent functional deficits in older adults.

Indexed as

Elective Surgical ProceduresRecovery of FunctionActivities of Daily LivingAgedAgingCohort StudiesDisability EvaluationFemaleHumansLongitudinal StudiesMaleMassachusettsPatient Readmissionagingcohort studyphysical functionreadmissionsurgery

Identifiers

PMID27898172
PMCPMC5258816
OpenAlexW2557935317

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.