Evidence map›Paper›PMID 27898031›Full record

ArticleInternational journal of molecular sciences2016

Inherited Variants in Wnt Pathway Genes Influence Outcomes of Prostate Cancer Patients Receiving Androgen Deprivation Therapy.

Jiun-Hung Geng, Victor C Lin, Chia-Cheng Yu, Chao-Yuan Huang, Hsin-Ling Yin, Ta-Yuan Chang, Te-Ling Lu, Shu-Pin Huang, Bo-Ying Bao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. WNT Pathway Mutations in Metachronous Oligometastatic Castration-Sensitive Prostate Cancer.International journal of radiation oncology, biology, physics · 2023
    Article
  6. Article
  7. Biomedicines · 2021
    Article
  8. Review
  9. Clinical characteristics andWorld journal of clinical cases · 2021
    Article
  10. Article
  11. Article
  12. WNT signalling in prostate cancer.Nature reviews. Urology · 2017
    Review
  13. Article
  14. Cancer genomics & proteomics
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jiun-Hung GengDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. u9001090@hotmail.com.
Victor C LinDepartment of Urology, E-Da Hospital, Kaohsiung 824, Taiwan. victorlin0098@yahoo.com.tw.
Chia-Cheng YuDivision of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan. ccyu@vghks.gov.tw.
Chao-Yuan HuangDepartment of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 100, Taiwan. cyhuang0909@ntu.edu.tw.
Hsin-Ling YinDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. schoolyin@gmail.com.
Ta-Yuan ChangDepartment of Occupational Safety and Health, China Medical University, Taichung 404, Taiwan. tychang@mail.cmu.edu.tw.
Te-Ling LuDepartment of Pharmacy, China Medical University, Taichung 404, Taiwan. lutl@mail.cmu.edu.tw.
Shu-Pin HuangDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. shpihu@yahoo.com.tw.
Bo-Ying BaoDepartment of Pharmacy, China Medical University, Taichung 404, Taiwan. bao@mail.cmu.edu.tw.
Kaohsiung Medical University · TWChina Medical University · TWAsia University · TWE-Da Hospital · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant Wnt signaling has been associated with many types of cancer. However, the association of inherited Wnt pathway variants with clinical outcomes in prostate cancer patients receiving androgen deprivation therapy (ADT) has not been determined. Here, we comprehensively studied the contribution of common single nucleotide polymorphisms (SNPs) in Wnt pathway genes to the clinical outcomes of 465 advanced prostate cancer patients treated with ADT. Two SNPs,

Indexed as

Adenomatous Polyposis ColiAndrogen AntagonistsAntineoplastic Agents, HormonalDisease ProgressionGenotypeHumansMalePolymorphism, Single NucleotidePrognosisProstateProstatic NeoplasmsWnt Signaling PathwayAndrogen AntagonistsAntineoplastic Agents, Hormonalandrogen deprivation therapygenetic variationoutcomesprostate cancerWnt pathway

Identifiers

PMID27898031
PMCPMC5187770
OpenAlexW2558822674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.