Evidence map›Paper›PMID 27897325›Full record

ReviewExperimental dermatology2017

The biomarker landscape in mycosis fungoides and Sézary syndrome.

Brittany Dulmage, Larisa Geskin, Joan Guitart, Oleg E Akilov

Open access · bronzeAbstract readReview
In one paragraph

Review in Experimental dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Cutaneous T cell lymphoma.Nature reviews. Disease primers · 2021
    Review
  13. Cutaneous T cell lymphoma.Nature reviews. Disease primers · 2021
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Brittany DulmageDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA.
Larisa GeskinDepartment of Dermatology, Columbia University, New York, NY, USA.
Joan GuitartDepartment of Dermatology, Northwestern University, Chicago, IL, USA.
Oleg E AkilovDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-1339-5710
University of Pittsburgh · USColumbia University · USNorthwestern University · US

Funding

Therapuetic Immune Targeting of EphA2 Expressed by Melanoma & Its Tumor-AssociateP50CA121973 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KIRKWOOD, JOHN MUNN · 2008 to 2018
$22.9M
NCI NIH HHS P50 CA121973
6 · The paper itself

Abstract

The practice of pre-emptive individualized medicine is predicated on the discovery, development and application of biomarkers in specific clinical settings. Mycosis fungoides and Sézary syndrome are the two most common type of cutaneous T-cell lymphoma, yet diagnosis, prognosis and disease monitoring remain a challenge. In this review, we discuss the current state of biomarker discovery in mycosis fungoides and Sézary syndrome, highlighting the most promising molecules in different compartments. Further, we emphasize the need for continued multicentre efforts to validate available and new biomarkers and to develop prospective combinatorial panels of already discovered molecules.

Indexed as

BiomarkersGene ExpressionHumansMycosis FungoidesSezary SyndromeBiomarkerscell surface markercutaneous T-cell lymphomagene expressionscreeningsecretory protein

Identifiers

PMID27897325
PMCPMC5489366
OpenAlexW2559460869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.