Evidence map›Paper›PMID 27897263›Full record

ArticleScientific reports2016

Principal function of mineralocorticoid signaling suggested by constitutive knockout of the mineralocorticoid receptor in medaka fish.

Tatsuya Sakamoto, Madoka Yoshiki, Hideya Takahashi, Masayuki Yoshida, Yukiko Ogino, Toshitaka Ikeuchi, Tomoya Nakamachi, Norifumi Konno, Kouhei Matsuda, Hirotaka Sakamoto

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 41 citations in OpenAlex.

  1. Rainbow Trout (International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Tatsuya SakamotoUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, 701-4303, Japan.
Madoka YoshikiUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, 701-4303, Japan.
Hideya TakahashiUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, 701-4303, Japan.
Masayuki YoshidaLaboratory of Fish Physiology, Graduate School of Biosphere Science, Hiroshima University, Higashihiroshima, 739-8528, Japan.
Yukiko OginoGraduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 819-0395, Japan.
Toshitaka IkeuchiDepartment of Bioscience, Faculty of Bioscience, Nagahama Institute of Bio-Science and Technology, Nagahama, 526-0829, Japan.
Tomoya NakamachiLaboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama, Toyama, 930-8555, Japan.
Norifumi KonnoLaboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama, Toyama, 930-8555, Japan.
Kouhei MatsudaLaboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama, Toyama, 930-8555, Japan.
Hirotaka SakamotoUshimado Marine Institute, Faculty of Science, Okayama University, Setouchi, 701-4303, Japan.
Okayama University · JPUniversity of Toyama · JPHiroshima University · JPKyushu University · JPNagahama Institute of Bio-Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As in osmoregulation, mineralocorticoid signaling is implicated in the control of brain-behavior actions. Nevertheless, the understanding of this role is limited, partly due to the mortality of mineralocorticoid receptor (MR)-knockout (KO) mice due to impaired Na

Indexed as

AnimalsBehavior, AnimalBrainEyeLocomotionMineralocorticoidsOryziasOsmoregulationReceptors, MineralocorticoidSignal TransductionVisual PerceptionMineralocorticoidsReceptors, Mineralocorticoid

Identifiers

PMID27897263
PMCPMC5126551
OpenAlexW2557407637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.