Evidence map›Paper›PMID 27896815›Full record

ReviewThe Journal of physiology2017

How and why are calcium currents curtailed in the skeletal muscle voltage-gated calcium channels?

Bernhard E Flucher, Petronel Tuluc

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Voltage-sensing domains: structural and functional diversity.European biophysics journal : EBJ · 2026
    Review
  2. Article
  3. Article
  4. CaNature communications · 2024
    Article
  5. Article
  6. Case report: Dihydropyridine receptor (Frontiers in neurology · 2024
    Article
  7. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.British journal of pharmacology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Skeletal muscle CaPflugers Archiv : European journal of physiology · 2020
    Review
  15. Postsynaptic CaScientific reports · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. Anti-Cancer Agents in Proliferation and Cell Death: The Calcium Connection.International journal of molecular sciences · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Bernhard E FlucherDepartment of Physiology and Medical Physics, Medical University Innsbruck, Austria.ORCID 0000-0002-5255-4705
Petronel TulucPharmacology and Toxicology, Institute of Pharmacy, University of Innsbruck, Austria.ORCID 0000-0003-3660-6138
Innsbruck Medical University · ATUniversität Innsbruck · AT

Funding

Austrian Science Fund FWF F 4406Austrian Science Fund FWF P 23479Austrian Science Fund FWF P 27031Austrian Science Fund FWF W 1101
6 · The paper itself

Abstract

Voltage-gated calcium channels represent the sole mechanism converting electrical signals of excitable cells into cellular functions such as contraction, secretion and gene regulation. Specific voltage-sensing domains detect changes in membrane potential and control channel gating. Calcium ions entering through the channel function as second messengers regulating cell functions, with the exception of skeletal muscle, where Ca

Indexed as

AnimalsCalciumCalcium Channels, L-TypeHumansMuscle, SkeletalMuscular DiseasesProtein ConformationCalciumCalcium Channels, L-Type

Identifiers

PMID27896815
PMCPMC5330888
OpenAlexW2558030741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.