Evidence map›Paper›PMID 27896667›Full record

ArticleHead and neck pathology2017

Head and Neck Rhabdomyosarcoma: Clinical and Pathologic Characterization of Seven Cases.

Eleanor Chen, Robert Ricciotti, Neal Futran, Dolphine Oda

Open access · greenAbstract read
In one paragraph

Article in Head and neck pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Eleanor ChenDepartment of Pathology, University of Washington, 1959 Pacific Street, NE, Box 357705, Seattle, WA, 98195, USA. eleanor2@uw.edu.ORCID http://orcid.org/0000-0003-4372-7560
Robert RicciottiDepartment of Pathology, University of Washington, 1959 Pacific Street, NE, Box 357705, Seattle, WA, 98195, USA.
Neal FutranDepartment of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, USA.
Dolphine OdaDepartment of Oral & Maxillofacial Surgery, University of Washington School of Dentistry, Seattle, WA, 98195-7133, USA. doda@uw.edu.
University of Washington · USSeattle Pacific University · US

Funding

Characterizing Histone Deacetylases in RhabdomyosarcomaR01CA196882 · NCI · UNIVERSITY OF WASHINGTON · PI CHEN, ELEANOR Y · 2016 to 2020
$1.6M
Druggable Pathways Regulating Self-Renewal in Muscle and Rhabdomyosarcoma.K08AR063165 · NIAMS · UNIVERSITY OF WASHINGTON · PI CHEN, ELEANOR Y · 2012 to 2016
$694k
NCI NIH HHS R01 CA196882NIAMS NIH HHS K08 AR063165
6 · The paper itself

Abstract

Head and neck rhabdomyosarcoma occurs frequently in children and adolescents, and has been well studied in that population. In contrast, it is rare in adults and is not as well characterized clinically and pathologically. Seven cases of adult rhabdomyosarcoma occurring in head and neck were retrieved from the archives of Department of Pathology and Division of Oral Pathology at University of Washington. Radiologic findings and clinical history, as well as pathologic findings from hematoxylin and eosin slides and immunohistochemistry for myogenic markers were reviewed. A total of seven cases of rhabdomyosarcoma (two embryonal, three alveolar and two pleomorphic subtype) were reviewed. Patient ages ranged from 18 to 57 years (median 21 years). Classic and unique histologic features for each subtype, including post-treatment morphologic changes, were identified. Clinical follow-up information was available for 4 patients. 3 of 4 patients experienced recurrence, including two with distant metastasis. One patient died of disease progression 41 months after presentation. Head and neck rhabdomyosarcoma in adults can manifest both classic and unique histologic features for each subtype. In addition, recurrence and distant metastasis were observed, suggesting aggressive clinical behavior regardless of subtype.

Indexed as

AdolescentAdultFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedRhabdomyosarcomaYoung AdultAlveolarEmbryonalHead and neckPleomorphicRhabdomyosarcoma

Identifiers

PMID27896667
PMCPMC5550390
OpenAlexW2558521320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.