Evidence map›Paper›PMID 27896621›Full record

ArticleFrontiers of medicine2016

Distinct roles of ASIC3 and TRPV1 receptors in electroacupuncture-induced segmental and systemic analgesia.

Juanjuan Xin, Yangshuai Su, Zhaokun Yang, Wei He, Hong Shi, Xiaoyu Wang, Ling Hu, Xiaochun Yu, Xianghong Jing, Bing Zhu

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Frontiers of medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Moxibustion for Primary Dysmenorrhea: An Adjuvant Therapy for Pain Relief.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  11. Review
  12. Analgesia for Sheep in Commercial Production: Where to Next?Animals : an open access journal from MDPI · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Juanjuan XinInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Yangshuai SuInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Zhaokun YangInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Wei HeInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Hong ShiInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Xiaoyu WangInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Ling HuInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Xiaochun YuInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Xianghong JingInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China. jxhtjb@263.net.
Bing ZhuInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, 100700, China. zhubing@mail.cintcm.ac.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated the effects of different afferent fibers on electroacupuncture (EA)-induced analgesia. However, contributions of functional receptors expressed on afferent fibers to the EA analgesia remain unclear. This study investigates the roles of acid-sensing ion channel 3 (ASIC3) and transient receptor potential vanilloid 1 (TRPV1) receptors in EA-induced segmental and systemic analgesia. Effects of EA at acupoint ST36 with different intensities on the C-fiber reflex and mechanical and thermal pain thresholds were measured among the ASIC3

Indexed as

Acid Sensing Ion ChannelsAcupuncture PointsAnalgesiaAnimalsElectroacupunctureMaleMiceMice, Inbred C57BLMice, KnockoutNerve Fibers, UnmyelinatedPain ManagementTRPV Cation ChannelsAcid Sensing Ion ChannelsASIC3 protein, mouseTRPV1 protein, mouseTRPV Cation ChannelsanalgesiaASIC3C-fiber reflexelectroacupunctureTRPV1

Identifiers

PMID27896621
OpenAlexW2559047507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.