Evidence map›Paper›PMID 27896496›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2017

Dalbavancin reduces biofilms of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE).

D Knafl, S Tobudic, S C Cheng, D R Bellamy, F Thalhammer

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Dalbavancin-resistantJAC-antimicrobial resistance · 2024
    Article
  6. Review
  7. Article
  8. AInsects · 2022
    Article
  9. Dalbavancin in clinical practice: a particular place for the elderly?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Novel dalbavancin-PLLA implant coating prevents hematogenousFrontiers in bioengineering and biotechnology · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Antimicrobial agents and chemotherapy · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

D KnaflDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. daniela.knafl@meduniwien.ac.at.
S TobudicDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
S C ChengDunedin School of Medicine, University of Otago, Dunedin, New Zealand.
D R BellamyDunedin School of Medicine, University of Otago, Wellington, New Zealand.
F ThalhammerDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Medical University of Vienna · ATUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activity of dalbavancin against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE) in biofilm was investigated and the microbicidal biofilm concentrations (MBC) were determined. Biofilms obtained from ten MRSA and ten MRSE bloodstream isolates, collected from patients in the General Hospital of Vienna between 2012 and 2015, were incubated with dalbavancin in trypticase soy broth (TSB) in serial dilution from 0.0625 mg/l to 256 mg/l using a microtiter plate biofilm model. The plates were incubated for 24 h at 37 ° C and 50% humidity. Biofilms were fixed with 2.5% glutaraldehyde and stained with crystal violet. Subsequently the optical density (OD

Indexed as

Methicillin ResistanceAnti-Bacterial AgentsAustriaBacteremiaBiofilmsColorimetryGentian VioletHospitals, GeneralHumansMicrobial Sensitivity TestsMicrobial ViabilityStaining and LabelingStaphylococcus aureusStaphylococcus epidermidisTeicoplaninAnti-Bacterial AgentsdalbavancinGentian VioletTeicoplanin

Identifiers

PMID27896496
PMCPMC5366172
OpenAlexW2557986812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.