Evidence map›Paper›PMID 27896408›Full record

ArticleWorld journal of surgery2017

Is Routine Prophylactic Cholecystectomy Necessary During Gastrectomy for Gastric Cancer?

Jun Kimura, Chikara Kunisaki, Ryo Takagawa, Hirochika Makino, Michio Ueda, Mitsuyoshi Ota, Mari Oba, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo

Abstract read
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In one paragraph

Article in World journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. The Cholegas trial: long-term results of prophylactic cholecystectomy during gastrectomy for cancer-a randomized-controlled trial.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Early gastric cancer: A challenge in Western countries.World journal of gastroenterology · 2022
    Article
  10. Article
  11. Article
  12. Preservation of hepatic branch of the vagus nerve reduces the risk of gallstone formation after gastrectomy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jun KimuraDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan. kimjun77jp@yahoo.co.jp.
Chikara KunisakiDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Ryo TakagawaDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Hirochika MakinoDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Michio UedaDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Mitsuyoshi OtaDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Mari ObaDepartment of Biostatistics and Epidemiology, Graduate School of Medicine, Yokohama City University Medical Center, Yokohama, Japan.
Takashi KosakaDepartment of Gastroenterological Surgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Hirotoshi AkiyamaDepartment of Gastroenterological Surgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Itaru EndoDepartment of Gastroenterological Surgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Yokohama City University · JPYokohama City University Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerforming routine prophylactic cholecystectomy during gastrectomy in gastric cancer patients has been controversial. The frequency of cholelithiasis, cholecystitis, and cholangitis after gastrectomy has not been reported for large patient populations, so we carried out this retrospective study to aid the assessment of the necessity for prophylactic cholecystectomy.

methodsThis retrospective study reviewed 969 patients with gastric cancer who underwent distal gastrectomies with Billroth I reconstructions (DG) or total gastrectomies with Roux-en-Y reconstructions (TG), preserving the gallbladder, between January 2000 and May 2012. Risk factors for cholelithiasis, cholecystitis, and cholangitis after gastrectomy were evaluated using logistic regression analysis.

resultsThe median follow-up period after gastrectomy was 48 months (range 12-159 months). After gastrectomy, cholelithiasis occurred in 6.1% (59/969) patients and cholecystitis and/or cholangitis occurred in 1.2% (12/969) patients. The method used for gastrectomy was an independent risk factor for both cholelithiasis (TG/DG: OR (95%CI): 1.900 (1.114-3.240), p = 0.018) and cholecystitis and/or cholangitis (TG/DG: OR (95%CI): 8.325 (1.814-38.197), p = 0.006). In patients who developed cholelithiasis, the incidence of cholecystitis and/or cholangitis was 31.3% (10/32) after TG, but only 7.4% after DG.

conclusionsProphylactic cholecystectomy may be unnecessary in distal gastrectomy with Billroth I reconstruction.

Indexed as

AdultAgedAged, 80 and overCholecystectomyFemaleGallbladder DiseasesGastrectomyGastroenterostomyHumansMaleMiddle AgedRetrospective StudiesRisk FactorsStomach Neoplasms

Identifiers

PMID27896408
OpenAlexW4253508660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.