Evidence map›Paper›PMID 27896114›Full record

ArticleMolecular genetics and metabolism reports2014

Mitochondrial damage and cholesterol storage in human hepatocellular carcinoma cells with silencing of

Carlos R Morales, Lubov S Grigoryeva, Xuefang Pan, Luigi Bruno, Gilles Hickson, Michael H Ngo, Christopher R McMaster, Mark E Samuels, Alexey V Pshezhetsky

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Functional study of SCCD pathogenic geneMolecular medicine reports · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carlos R MoralesDepartment of Anatomy and Cell Biology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
Lubov S GrigoryevaCHU Sainte-Justine Research Center, Montreal, Quebec, Canada.
Xuefang PanCHU Sainte-Justine Research Center, Montreal, Quebec, Canada.
Luigi BrunoCHU Sainte-Justine Research Center, Montreal, Quebec, Canada.
Gilles HicksonCHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Department of Pathology and Cell Biology, University of Montreal, Montreal, Quebec, Canada.
Michael H NgoDepartment of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
Christopher R McMasterDepartment of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
Mark E SamuelsCHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Department of Medicine, University of Montreal, Montreal, Quebec, Canada.
Alexey V PshezhetskyDepartment of Anatomy and Cell Biology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; CHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Departments of Paediatrics and Biochemistry, University of Montreal, Montreal, Quebec, Canada.
Centre Hospitalier Universitaire Sainte-Justine · CADalhousie University · CAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterozygous mutations in the

Indexed as

CholesterolCoQ10MitochondrionReactive oxygen speciesSchnyder corneal dystrophy

Identifiers

PMID27896114
PMCPMC5121353
OpenAlexW1986484281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.