Evidence map›Paper›PMID 27896111›Full record

ArticleMolecular genetics and metabolism reports2014

Development of catecholamine and cortisol stress responses in zebrafish.

Kaoru Eto, Jaime K Mazilu-Brown, Nicole Henderson-MacLennan, Katrina M Dipple, Edward R B McCabe

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Understanding acute stress-mediated immunity in teleost fish.Fish and shellfish immunology reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kaoru EtoDepartment of Pediatrics, University of California, Los Angeles, USA; Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan.
Jaime K Mazilu-BrownDepartment of Bioengineering, University of California, Los Angeles, USA.
Nicole Henderson-MacLennanDepartment of Pediatrics, University of California, Los Angeles, USA.
Katrina M DippleDepartment of Pediatrics, University of California, Los Angeles, USA; Department of Human Genetics, University of California, Los Angeles, USA.
Edward R B McCabeDepartment of Pediatrics, University of California, Los Angeles, USA; Department of Bioengineering, University of California, Los Angeles, USA; Department of Human Genetics, University of California, Los Angeles, USA; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
University of California, Los Angeles · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus-pituitary-adrenal (HPA) axis and the sympathetic-adrenomedullary system, though the correlation with activation and development is not well understood. We evaluated the stress response of both cortisol and catecholamines during development in zebrafish. Zebrafish at two different stages of development were stressed in one of two different ways and cortisol and catecholamine were measured. Cortisol was measured by enzyme immune assay and catecholamine was measured by ELISA. Our results show that stress responses are delayed until after the synthesis of both cortisol and catecholamines. These observations suggest that the development of HPA axis may be required for the acquisition of the stress response for cortisol and catecholamines.

Indexed as

CatecholaminesCortisolHPA axisStress responseZebrafish

Identifiers

PMID27896111
PMCPMC5121345
OpenAlexW2023496428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.