Evidence map›Paper›PMID 27896051›Full record

ArticleApplied & translational genomics2012

Screening of mutations affecting protein stability and dynamics of FGFR1-A simulation analysis.

C George Priya Doss, B Rajith, Nimisha Garwasis, Pretty Raju Mathew, Anand Solomon Raju, K Apoorva, Denise William, N R Sadhana, Tanwar Himani, I P Dike

Open access · hybridAbstract read
In one paragraph

Article in Applied & translational genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

C George Priya DossCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
B RajithCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
Nimisha GarwasisCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
Pretty Raju MathewCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
Anand Solomon RajuCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
K ApoorvaCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
Denise WilliamCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
N R SadhanaCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
Tanwar HimaniCentre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India.
I P DikeDepartment of Biological Sciences, Covenant University, Nigeria.
Vellore Institute of Technology University · INCovenant University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single amino acid substitutions in Fibroblast Growth Factor Receptor 1 (

Indexed as

FGFR1FGFR1, Fibroblast growth factor type 1GD, Grantham DeviationGV, Grantham VarianceMolecular dynamics simulationMSA, Multiple Sequence AlignmentsNCBI, National Center for Biological InformationOMIM, Online Mendelian Inheritance in ManPolyPhen 2.0, Polymorphism PhenotypingRI, Reliability IndexRMSD, Root Mean Square DeviationRMSF, Root Mean Square FluctuationSIFT, Sorting Intolerant From TolerantSNAP, Screening for Non acceptable PolymorphismsSNPsSNPs, Single Nucleotide PolymorphismsSPC, Simple Point Charge

Identifiers

PMID27896051
PMCPMC5121281
OpenAlexW1986891519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.