Evidence map›Paper›PMID 27896016›Full record

ArticleBiomedical optics express2016

Wide-field Fourier ptychographic microscopy using laser illumination source.

Jaebum Chung, Hangwen Lu, Xiaoze Ou, Haojiang Zhou, Changhuei Yang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 77 citations in OpenAlex.

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  12. Motion-corrected Fourier ptychography.Biomedical optics express · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jaebum ChungDepartment of Electrical Engineering, California Institute of Technology, Pasadena, California, 91125, USA.
Hangwen LuDepartment of Electrical Engineering, California Institute of Technology, Pasadena, California, 91125, USA.
Xiaoze OuDepartment of Electrical Engineering, California Institute of Technology, Pasadena, California, 91125, USA.
Haojiang ZhouDepartment of Electrical Engineering, California Institute of Technology, Pasadena, California, 91125, USA.
Changhuei YangDepartment of Electrical Engineering, California Institute of Technology, Pasadena, California, 91125, USA.
California Institute of Technology · US

Funding

Multiplex fluorescence optofluidic microscopy for diagnosis of enteric parasitesR01AI096226 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI YANG, CHANGHUEI · 2011 to 2015
$5.8M
NIAID NIH HHS R01 AI096226
6 · The paper itself

Abstract

Fourier ptychographic (FP) microscopy is a coherent imaging method that can synthesize an image with a higher bandwidth using multiple low-bandwidth images captured at different spatial frequency regions. The method's demand for multiple images drives the need for a brighter illumination scheme and a high-frame-rate camera for a faster acquisition. We report the use of a guided laser beam as an illumination source for an FP microscope. It uses a mirror array and a 2-dimensional scanning Galvo mirror system to provide a sample with plane-wave illuminations at diverse incidence angles. The use of a laser presents speckles in the image capturing process due to reflections between glass surfaces in the system. They appear as slowly varying background fluctuations in the final reconstructed image. We are able to mitigate these artifacts by including a phase image obtained by differential phase contrast (DPC) deconvolution in the FP algorithm. We use a 1-Watt laser configured to provide a collimated beam with 150 mW of power and beam diameter of 1 cm to allow for the total capturing time of 0.96 seconds for 96 raw FPM input images in our system, with the camera sensor's frame rate being the bottleneck for speed. We demonstrate a factor of 4 resolution improvement using a 0.1 NA objective lens over the full camera field-of-view of 2.7 mm by 1.5 mm.

Indexed as

(070.0070) Fourier optics and signal processing(110.1758) Computational imaging(180.0180) Microscopy

Identifiers

PMID27896016
PMCPMC5119616
OpenAlexW2963166995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.