Evidence map›Paper›PMID 27895976›Full record

ArticleWorld journal of gastrointestinal pathophysiology2016

Microscopic colitis in patients with mild duodenal damage: A new clinical and pathological entity ("lymphocytic enterocolitis")?

Gabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Sharmila Fagoonee, Nicoletta Sapone, Gian Paolo Caviglia, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano

Open access · diamondAbstract read
In one paragraph

Article in World journal of gastrointestinal pathophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gabriele Antonio BonaguraGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Davide Giuseppe RibaldoneGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Sharmila FagooneeGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Nicoletta SaponeGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Gian Paolo CavigliaGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Giorgio Maria SaraccoGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Marco AstegianoGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
Rinaldo PellicanoGabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Nicoletta Sapone, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano, Unit of Gastroenterology and Hepatology, Molinette Hospital, 10126 Torino, Italy.
University of Turin · ITFondazione Ricerca Molinette · ITCreative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the potential association between mild duodenal damage and microscopic colitis (MC).

methodsWe retrospectively included 105 consecutive patients with type I Marsh-Oberhuber duodenal damage and negativity for immunoglobulin A anti-endomysium and anti-tissue transglutaminase. The following parameters were analyzed: Sex, age at execution of esophagogastroduodenoscopy, duodenal damage, and number of intraepithelial lymphocytes at biopsies, prevalence of

resultsColonoscopy was performed in 59 patients, but only in 48 of them biopsies were taken in the entire colon. Considering the latter cohort, the diagnosis of MC was met in 25 (52.1%) patients while in 18 patients other pathologic findings were reported: 13 (27%) cases of nonspecific inflammatory bowel disease, 2 (4.2%) cases of Crohn's disease, 2 (4.2%) cases of eosinophilic gastroenteritis, and 1 (2.1%) case of autoimmune enteritis. Five (10.4%) patients had a normal colonoscopic result. Matching the groups by age, and considering only patients who underwent colonoscopy (42.7 ± 15.5 years)

conclusionMild duodenal damage is associated with MC in more than half of the cases. This association supports the hypothesis of a link between these two entities.

Indexed as

Autoimmune diseasesCeliac diseaseHelicobacter pyloriIntraepithelial lymphocytesLymphocytic colitisLymphocytic enterocolitisMicroscopic colitis

Identifiers

PMID27895976
PMCPMC5108976
OpenAlexW2549382376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.