ReviewClinical and translational allergy2016
Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy ageing) and the Global Alliance against Chronic Respiratory Diseases (GARD), a World Health Organization GARD research demonstration project.
Registry-linked trialAbstract readReview
In one paragraph
Review in Clinical and translational allergy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05786638 (Efficacy of Sublingual Versus Subcutaneous Allergen Immunotherapy in Patients With Bronchial Asthma), which is not on this map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Sublingual Versus Subcutaneous Allergen Immunotherapy in Patients With Bronchial Asthma
Who cites it
8 citing papers in PubMed.
- Intralymphatic immunotherapy with birch and grass pollen extracts. A randomized double-blind placebo-controlled clinical trial.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023Trial
- Seven Steps in Seven Days to Managing Allergy in the Tropics.Research and reports in tropical medicine · 2025Article
- Clinical and experimental treatment of allergic asthma with an emphasis on allergen immunotherapy and its mechanisms.Clinical and experimental immunology · 2023Article
- Review
- Turkish Guideline for Diagnosis and Treatment of Allergic Rhinitis (ART).Turkish archives of otorhinolaryngology · 2021Article
- Allergen Immunotherapy for Local Respiratory Allergy.Current allergy and asthma reports · 2020Review
- Immunotherapy of mold allergy: A review.Human vaccines & immunotherapeutics · 2017Review
- CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report.Clinical and translational allergy · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
67 authors.
M A CalderonNational Heart and Lung Institute, Royal Brompton Hospital NHS, Imperial College London, London, UK.
P DemolyUnité d'allergologie, Département de Pneumologie et AddictologieHôpital Arnaud de Villeneuve, CHRU de Montpellier, Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, 75013 Paris, France.
T CasaleUniversity of South Florida Morsani College of Medicine, Tampa, FL USA.
C A AkdisChristine Kühne Center for Allergy Research and Education (CK-CARE), Swiss Institute of Allergy and Asthma Research (SIAF)University of Zurich, Davos, Switzerland.
C BachertUpper Airways Research Laboratory (URL), ENT Department, University Hospital Ghent, Ghent, Belgium.
M BewickiQ4U consultants Ltd, London, UK.
B M BilòAllergy Unit, Department of Internal Medicine, University Hosp Ospedali Riuniti, Ancona, Italy.
B BohleDepartment of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
S BoniniSecond University of Naples and IFT-CNR, Rome, Italy.
A BushNational Heart and Lung Institute, Royal Brompton Hospital NHS, Imperial College London, London, UK.
D P CaimmiUnité d'allergologie, Département de Pneumologie et AddictologieHôpital Arnaud de Villeneuve, CHRU de Montpellier, Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, 75013 Paris, France.
G W CanonicaAllergy and Respiratory Diseases Clinic, DIMI, University of Genoa, IRCCS AOU San Martino-IST, Genoa, Italy.
V CardonaAllergy Section, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
A M ChiriacDivision of Allergy, Hôpital Arnaud de Villeneuve, Department of Pulmonology, University Hospital of Montpellier, Montpellier - UPMC Univ Paris 06, UMRS 1136, Equipe - EPAR - IPLESP, Sorbonne Universités, Paris, France.
L CoxNova Southeastern University, Ft. Lauderdale, FL USA.
A CustovicNational Heart and Lung Institute, Royal Brompton Hospital NHS, Imperial College London, London, UK.
F De BlayAllergy Division, Chest Disease Department, University Hospital of Strasbourg, Strasbourg, France.
P DevillierUniversity Versailles Saint-Quentin and Clinical Pharmacology Unit, UPRES EA 220, Department of Airway Diseases, Foch Hospital, Suresnes, France.
A DidierRespiratory Diseases Department, Rangueil-Larrey Hospital, Toulouse, France.
G Di LorenzoDipartimento BioMedico di Medicina Interna e Specialistica (Di.Bi.M.I.S), University of Palermo, Palermo, Italy.
G Du ToitGuy's and St. Thomas' NHS Trust, Kings College, London, UK.
S R DurhamAllergy and Clinical Immunology Section, National Heart and Lung Institute, Imperial College London, London, UK.
P EngDepartment of Pediatric Pulmonology and Allergy, Children's Hospital, Aarau, Switzerland.
A FiocchiDivision of Allergy, Department of Pediatrics, Bambino Gesù Pediatric Hospital, Vatican City, Rome, Italy.
A T FoxKing's College London Allergy Academy, London, UK.
R Gerth van WijkSection of Allergology, Department of Internal Medicine, Erasmus Medical Center, Building Rochussenstraat, Rotterdam, The Netherlands.
R M GomezUnidad Alergia and Asma, Hospital San Bernardo, Salta, Argentina.
T HaathelaSkin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.
S HalkenHans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark.
P W HellingsClinical Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, KU Leuven, Louvain, Belgium.
L JacobsenAllergy Learning and Consulting, Secretary Immunotherapy Interest Group EAACI, Copenhagen, Denmark.
J JustAllergology Department, Centre de l'Asthme et des Allergies, Hôpital d'Enfants Armand-Trousseau, INSERM, UMR_S 1136, Sorbonne Universités, UPMC Univ Paris, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe EPAR, Paris, France.
L K TannoHospital Sírio Libanês, São Paulo, Brazil ; University Hospital of Montpellier, Montpellier, France ; UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Sorbonne Universités, Paris, France.
J Kleine-TebbeAllergy and Asthma Center Westend, Outpatient Clinic and Clinical Research Center, Ackermann, Hanf, & Kleine-Tebbe, Berlin, Germany.
L KlimekCenter for Rhinology and Allergology, German Society for Otorhinolaryngology HNS, Wiesbaden, Germany.
E F KnolDepartments of Immunology and Dermatology/Allergology, University Medical Center Utrecht, Heidelberglaan, Utrecht, The Netherlands.
P KunaMedical University of Lodz, Lodz, Poland.
D E Larenas-LinnemannARIA, Mexico, DF Mexico ; AAAAI, Hospital Médica Sur, Mexico, DF Mexico.
A LinnebergResearch Centre for Prevention and Health, The Capital Region of Denmark, Copenhagen, Denmark ; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark ; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
M MatricardiPediatric Pneumology and Immunology, Charité Medical University, Berlin, Germany.
H J MallingDanish Allergy Centre, Allergy Clinic, Gentofte University Hospital, Hellerup, Denmark.
R MoesgesIMSIE, Klinikum der Universität zu Köln A. ö. R., Cologne, Germany.
J MullolUnitat de Rinologia i Clínica de l'Olfacte, ENT Department, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, Barcelona, Catalonia Spain.
A MuraroDepartment of Women and Child Health, Food Allergy Referral Centre Veneto Region, Padua General University Hospital, Padua, Italy.
N PapadopoulosAllergy Unit, 2nd Pediatric Clinic, University of Athens, Athens, Greece.
G PassalacquaAllergy and Respiratory Diseases, IRCCS San Martino-IST, Univesity of Genoa, Genoa, Italy.
E PastorelloASST Grande Ospedale Metropolitano Niguarda, P.zza Ospedale Maggiore, Milan, Italy.
O PfaarDepartment of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Mannheim, Germany ; Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany ; Center for Rhinology and Allergology, Wiesbaden, Germany.
D PriceDivision of Applied Health Sciences, Primary Care Respiratory Medicine, Academic Primary Care, University of Aberdeen, Aberdeen, Scotland, UK ; Research in Real Life (RiRL), Oakington, Cambridge, UK ; Optimum Patient Care Ltd, Singapore, Singapore.
P Rodriguez Del RioAllergy Section, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
R RuëffDepartment of Dermatology and Allergology, Ludwig-Maximillian University, Munich, Germany.
B SamolinskiDepartment of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.
G K ScaddingRoyal National Throat, Nose and Ear Hospital, London, UK ; University College London, London, UK.
G SentiClinical Trials Center, University Hospital of Zurich, Zurich, Switzerland.
M H ShamjiImmunomodulation and Tolerance Group, Allergy and Clinical Immunology, Inflammation, Repair and Development Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK ; MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK.
A SheikhAsthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG UK.
J C SisulSLAAI, Asuncion, Paraguay.
D SolePrograma de Pòs-Graduação em Pediatria e Ciências Aplicadas à Pediatria, Departamento de Pediatria EPM, UNIFESP, São Paulo, Brazil.
G J SturmDepartment of Dermatology and Venerology, Medical University of Graz, Graz, Austria ; Allergy Outpatient Clinic Reumannplatz, Vienna, Austria.
A TabarServicio de Alergologia, Complejo Hospitalario de Navarra, Pamplona, Spain.
R Van ReeDepartments of Experimental Immunology and Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
M T VenturaUnit of Geriatric Immunoallergology, Interdisciplinary Department of Medicine, University of Bari Medical School, Bari, Italy.
C VidalAllergy Department, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
E M VargaRespiratory and Allergic Disease Division, Department of Paediatrics, Medical University of Graz, Graz, Austria.
M WormAllergie-Centrum-Charité, Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Berlin, Germany.
T ZuberbierAllergie-Centrum-Charité, Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Berlin, Germany.
J BousquetUniversity Hospital of Montpellier, Montpellier, France ; Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Paris, France ; INSERM, VIMA, U1168, Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, Paris, France ; UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Versailles Cedex, France ; CHRU, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing.
Indexed as
AgeingAIRWAYS ICPsAllergen immunotherapyAsthmaEIP on AHARhinitis
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
NCT05786638ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.