ArticleMalawi medical journal : the journal of Medical Association of Malawi2016
Severe anemia in Malawian children.
Article in Malawi medical journal : the journal of Medical Association of Malawi, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Use of point-of-care haemoglobin tests to diagnose childhood anaemia in low- and middle-income countries: A systematic review.Tropical medicine & international health : TM & IH · 2024Pooled it
- Post-discharge morbidity and mortality in children admitted with severe anaemia and other health conditions in malaria-endemic settings in Africa: a systematic review and meta-analysis.The Lancet. Child & adolescent health · 2022Pooled it
- Malaria Chemoprevention in the Postdischarge Management of Severe Anemia.The New England journal of medicine · 2020Trial
- The CYB5R3American journal of hematology · 2020Trial
- Survival and Predictors of Mortality Among Critically Ill Children Admitted to an Intensive Care Unit in a Resource-Limited Setting in Southeastern Ethiopia: A Prospective Cohort Study.Health science reports · 2026Article
- Increased Plasmodium falciparum EBA175RIII-V antibody titres despite a 13-month malaria mass testing, treatment, and tracking intervention in a high malaria endemic community in Ghana.Malaria journal · 2025Article
- Circulating Immune Complexes and Glucose-6-Phosphate Dehydrogenase Deficiency Predict Recurrent Blackwater Fever in Ugandan Children With Severe Malaria.The Journal of infectious diseases · 2025Article
- Association Between Plasmodium Infection and Blood Count Values: Implications for Malaria Diagnosis in Resource-Limited Settings.Acta parasitologica · 2025Article
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- Determinants of household-, maternal- and child-related factors associated with nutritional status among children under five in Mali: evidence from a Demographic and Health Survey, 2018.Public health nutrition · 2024Article
- Article
- Prevalence and Associated Risk Factors of Anemia Among Hospitalized Children in a Tertiary Level Hospital in Botswana.Global pediatric health · 2023Article
- Article
- Malaria-associated adhesion molecule activation facilitates the destruction of uninfected red blood cells.Blood advances · 2022Article
- The effect of malaria on haemoglobin concentrations: a nationally representative household fixed-effects study of 17,599 children under 5 years of age in Burkina Faso.Malaria journal · 2021Article
- Joint modelling of malaria and anaemia in children less than five years of age in Malawi.Heliyon · 2021Article
- "Satanism is witchcraft's younger sibling": Changing perceptions of natural and supernatural anaemia causality in Malawian children.PloS one · 2021Article
- Neurodevelopmental performance among pre-schoolers treated for severe anaemia at Lira Regional Referral Hospital, Uganda.PloS one · 2020Article
- Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection.Malaria journal · 2019Article
- Data needed to respond appropriately to anemia when it is a public health problem.Annals of the New York Academy of Sciences · 2019Article
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
backgroundSevere anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied.
methodsWe conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and 757 preschool children without severe anemia in urban and rural settings in Malawi. Causal factors previously associated with severe anemia were studied. The data were examined by multivariate analysis and structural equation modeling.
resultsBacteremia (adjusted odds ratio, 5.3; 95% confidence interval [CI], 2.6 to 10.9), malaria (adjusted odds ratio, 2.3; 95% CI, 1.6 to 3.3), hookworm (adjusted odds ratio, 4.8; 95% CI, 2.0 to 11.8), human immunodeficiency virus infection (adjusted odds ratio, 2.0; 95% CI, 1.0 to 3.8), the
conclusionsThere are multiple causes of severe anemia in Malawian preschool children, but folate and iron deficiencies are not prominent among them. Even in the presence of malaria parasites, additional or alternative causes of severe anemia should be considered.
Identifiers
27895843PMC5116999What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.