Evidence map›Paper›PMID 27895817›Full record

ReviewWorld journal of gastrointestinal oncology2016

Current noninvasive tests for colorectal cancer screening: An overview of colorectal cancer screening tests.

Le-Le Song, Yue-Min Li

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04628052 (The Effect of Music on Colonoscopy), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04628052 naterminatednot on this mapstarted 2020, after this paper: background citation

The Effect of Music on Colonoscopy (MUSICOL): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2020 to 2023Enrolled83ConditionsProcedural Anxiety, Colon PolypArmsColonoscopy
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.

  1. Diagnostic Performance of IntestinalChinese medical journal · 2018
    Pooled it
  2. Quantification of EctopicInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Advanced biomedical research · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Serum biomarkers REG1A and REG3A combined with the traditional CEA represent a novel nomogram for the screening and risk stratification of colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Reducing disparities and achieving health equity in colorectal cancer screening.Techniques and innovations in gastrointestinal endoscopy · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Le-Le SongLe-Le Song, Yue-Min Li, Department of Radiotherapy, the Chinese PLA 309 Hospital, Beijing 100091, China.
Yue-Min LiLe-Le Song, Yue-Min Li, Department of Radiotherapy, the Chinese PLA 309 Hospital, Beijing 100091, China.
Beijing Biocytogen (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) has become the third most common cancer in the world. Screening has been shown to be an effective way to identify early CRC and precancerous lesions, and to reduce its morbidity and mortality. Several types of noninvasive tests have been developed for CRC screening, including the fecal occult blood test (FOBT), the fecal immunochemical test (FIT), the fecal-based DNA test and the blood-based DNA test (the SEPT9 assay). FIT has replaced FOBT and become the major screening test due to high sensitivity, specificity and low costs. The fecal DNA test exhibited higher sensitivity than FIT but its current cost is high for a screening assay. The SEPT9 assay showed good compliance while its performance in screening needs further improvements. These tests exhibited distinct sensitivity and specificity in screening for CRC and adenoma. This article will focus on the performance of the current noninvasive

Indexed as

AdenomaColorectal cancerFecal DNAFecal immunochemical testSEPT9Septin 9

Identifiers

PMID27895817
PMCPMC5108981
OpenAlexW2556539181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.