Evidence map›Paper›PMID 27895771›Full record

ArticleOncology letters2016

Co-culture of hepatoma cells with hepatocytic precursor (stem-like) cells inhibits tumor cell growth and invasion by downregulating Akt/NF-κB expression.

Cheng-Jun Sui, Miao Xu, Wei-Qing Li, Jia-Mei Yang, Hong-Zhu Yan, Hui-Min Liu, Chun-Yan Xia, Hong-Yu Yu

Abstract read
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cheng-Jun SuiDepartment of Special Medical Care Unit I and Liver Transplantation, The Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, P.R. China.
Miao XuDepartment of Geratology, Changhai Hospital, Shanghai 200438, P.R. China.
Wei-Qing LiDepartment of Pathology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China.
Jia-Mei YangDepartment of Special Medical Care Unit I and Liver Transplantation, The Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, P.R. China.
Hong-Zhu YanDepartment of Pathology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China.
Hui-Min LiuDepartment of Pathology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China.
Chun-Yan XiaDepartment of Pathology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China.
Hong-Yu YuDepartment of Pathology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocytic stem cells (HSCs) have inhibitory effects on hepatocarcinoma cells. The present study investigated the effects of HSC activity in hepatocarcinoma cells

Indexed as

Akt/NF-κB signaling pathwaycancer metastasishepatocytic precursor (stem-like) cellshepatoma cells

Identifiers

PMID27895771
PMCPMC5104234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.