ArticleWorld journal of gastroenterology2016
Full-thickness myotomy is associated with higher rate of postoperative gastroesophageal reflux disease.
Article in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04578769 (Comparison Study of Conventional Peroral Endoscopic Myotomy), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison Study of Conventional Peroral Endoscopic Myotomy (POEM) and Different Modified Procedures of POEM for Achalasia
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- SAGES-EAES clinical practice guidelines for the use of FLIP/impedance planimetry in the surgical work-up and management of GERD, achalasia, and gastroparesis.Surgical endoscopy · 2026Guideline
- Risk factors for gastroesophageal reflux after POEM for achalasia: a systematic review and meta-analysis.Surgical endoscopy · 2021Pooled it
- Saudi Gastroenterology Association (SGA) clinical care pathway and standards of care for peroral endoscopic myotomy (POEM) in achalasia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Reflux after peroral endoscopic myotomy: The dilemma and the options.World journal of gastroenterology · 2025Article
- Gastroesophageal reflux after per-oral endoscopic myotomy: Management literature.World journal of gastroenterology · 2024Article
- Long-term efficacy of peroral endoscopic myotomy for achalasia under different criteria.Surgical endoscopy · 2024Article
- Prediction, prevention and management of gastroesophageal reflux after per-oral endoscopic myotomy: An update.World journal of gastroenterology · 2024Review
- Peroral Endoscopic Myotomy (POEM) and Laparoscopic Heller Myotomy with Dor Fundoplication for Esophagogastric Junction Outflow Obstruction (EGJOO): a Comparison of Outcomes and Impact on Physiology.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Clinical and financial outcomes of per-oral endoscopic myotomy compared to laparoscopic heller myotomy for treatment of achalasia.Surgical endoscopy · 2023Article
- Usefulness of EndoFLIP in Diverticular Peroral Endoscopic Myotomy for Symptomatic Epiphrenic Diverticulum.Journal of neurogastroenterology and motility · 2023Article
- Gastro-esophageal reflux disease (GERD) after peroral endoscopic myotomy (POEM).Surgical endoscopy · 2022Article
- Peroral endoscopic longerWorld journal of gastrointestinal surgery · 2022Article
- Impact of modified techniques on outcomes of peroral endoscopic myotomy: A narrative review.Frontiers in medicine · 2022Review
- Identification of independent risk factors for intraoperative gastroesophageal reflux in adult patients undergoing general anesthesia.World journal of clinical cases · 2021Article
- Per-oral endoscopic myotomy for palliation of achalasia: A video atlas.JTCVS techniques · 2021Article
- Long-term clinical results of per-oral endoscopic myotomy (POEM) for achalasia: First report of more than 10-year patient experience as assessed with a questionnaire-based survey.Endoscopy international open · 2021Article
- Peroral Endoscopic Myotomy for Esophageal Motility Disorders.Clinical endoscopy · 2020Article
- Peroral endoscopic myotomy for esophageal motility disorders.Esophagus : official journal of the Japan Esophageal Society · 2020Review
- Per-oral endoscopic myotomy and gastroesophageal reflux: Where do we stand after a decade of "POETRY"?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019Review
- 2007-2019: a "Third"-Space Odyssey in the Endoscopic Management of Gastrointestinal Tract Diseases.Current treatment options in gastroenterology · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare long-term occurrence of gastroesophageal reflux disease (GERD) between two different types of peroral endoscopic myotomy (POEM) for achalasia.
methodsWe included all patients with achalasia who underwent POEM at our hospital from August 2011 to October 2012 and had complete GERD evaluation with ≥ 3 years of follow-up. They were divided into circular or full-thickness myotomy groups according to the depth of myotomy. Demographics, Eckardt score, manometry results, 24-h pH monitoring, and GERD symptoms were recorded and compared between the two groups.
resultsWe studied 56 patients (32 circular myotomy and 24 full-thickness myotomy) with complete GERD evaluation. There was no significant difference between the two groups in terms of treatment success (defined as Eckardt score ≤ 3), postoperative Eckardt score, mean basal lower esophageal sphincter pressure, and 4-s integrated relaxation pressure (4sIRP). Postoperative abnormal esophageal acid exposure was found in 25 patients (44.6%). A total of 13 patients (23.2%) had GERD symptoms and 12 had esophagitis (21.4%). Clinically relevant GERD (abnormal esophageal acid exposure associated with GERD symptoms and/or esophagitis) was diagnosed in 13 patients (23.2%). Multivariate analysis revealed that full-thickness myotomy and low level of postoperative 4sIRP were predictive factors for clinically relevant GERD.
conclusionEfficacy and manometry are comparable between achalasia patients treated with circular or full-thickness myotomy. But patients with full-thickness myotomy and low postoperative 4sIRP have more GERD.
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