Observational studyWorld journal of gastroenterology2016
First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases.
Observational study in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03065465 (Randomized Controlled Trial), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Controlled Trial (RCT) of Standard Endoscopic Hemostasis Compared to OVESCO for Severe Non-variceal UGI Hemorrhage
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Clinical efficacy of the over-the-scope clip device: A systematic review.World journal of gastroenterology · 2020Pooled it
- Perforated and bleeding peptic ulcer: WSES guidelines.World journal of emergency surgery : WJES · 2020Guideline
- Clinical outcomes of over-the-scope-clip system for the treatment of acute upper non-variceal gastrointestinal bleeding: a systematic review and meta-analysis.BMC gastroenterology · 2019Pooled it
- Randomized Controlled Trial of Over-the-Scope Clip as Initial Treatment of Severe Nonvariceal Upper Gastrointestinal Bleeding.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021Trial
- Role of clips, devices and sprays in endoscopic hemostasis: An update (with videos).Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Review
- Over-the-Scope-Clip Iatrogenic Ligation of the Gastroduodenal Artery: A Case Report.The American journal of case reports · 2024Article
- Reduced mortality for over-the-scope clips (OTSC) versus surgery for refractory peptic ulcer bleeding: a retrospective study.Surgical endoscopy · 2023Article
- Hemostasis Techniques for Non-variceal Upper GI Hemorrhage: Beyond Injection and Cautery.Digestive diseases and sciences · 2022Review
- Over-the-scope clip versus transcatheter arterial embolization for refractory peptic ulcer bleeding-A propensity score matched analysis.United European gastroenterology journal · 2021Article
- Over-the-scope clip as first-line therapy for ulcers with high-risk bleeding stigmata is efficient compared to standard endoscopic therapy.Endoscopy international open · 2021Article
- Outcomes in Severe Upper GI Hemorrhage from Dieulafoy's Lesion with Monitoring of Arterial Blood Flow.Digestive diseases and sciences · 2021Article
- Over-The-Scope Clip system as a first-line therapy for high-risk bleeding peptic ulcers: a retrospective study.Surgical endoscopy · 2021Observational
- Use of over-the-scope clips in the colon in clinical practice: results from a German administrative database.Endoscopy · 2020Article
- Use of over-the-scope clip for ulcer hemostasis after failure of both surgery and interventional therapy: A case report.Medicine · 2020Article
- Endoscopic advances in the management of non-variceal upper gastrointestinal bleeding: A review.World journal of gastrointestinal endoscopy · 2020Review
- Over-the-scope clip vs epinephrine with clip for first-line hemostasis in non-variceal upper gastrointestinal bleeding: a propensity score match analysis.Endoscopy international open · 2020Article
- Use of the Endoscopic Clipping Over the Scope Technique to Treat Acute Severe Lower Gastrointestinal Bleeding in the Colon and Anal Transition Zone.Gastrointestinal endoscopy clinics of North America · 2020Review
- Devices for endoscopic hemostasis of nonvariceal GI bleeding (with videos).VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2019Article
- Over-the-scope clip in peptic ulcer bleeding: clinical success in primary and secondary treatment and factors associated with treatment failure.Endoscopy international open · 2019Article
- Safety and efficacy of over-the-scope clip-assisted full thickness resection of duodenal subepithelial tumors: A case report.World journal of gastrointestinal endoscopy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate rebleeding, primary failure (PF) and mortality of patients in whom over-the-scope clips (OTSCs) were used as first-line and second-line endoscopic treatment (FLET, SLET) of upper and lower gastrointestinal bleeding (UGIB, LGIB).
methodsA retrospective analysis of a prospectively collected database identified all patients with UGIB and LGIB in a tertiary endoscopic referral center of the University of Freiburg, Germany, from 04-2012 to 05-2016 (
resultsPrimary hemostasis and clinical success of bleeding lesions (without rebleeding) was achieved in 88/100 (88%) and 78/100 (78%), respectively. PF was significantly lower when OTSCs were applied as FLET compared to SLET (4.9%
conclusionOur data show for the first time that FLET with OTSC might be the best predictor to successfully prevent rebleeding of gastrointestinal bleeding compared to SLET. The type of treatment determines the success of primary hemostasis or primary failure.
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Registered trials
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