Evidence map›Paper›PMID 27895384›Full record

ArticleJournal of clinical biochemistry and nutrition2016

Exendin-4 induces extracellular-superoxide dismutase through histone H3 acetylation in human retinal endothelial cells.

Hiroyuki Yasuda, Atsuko Ohashi, Shohei Nishida, Tetsuro Kamiya, Tetsuya Suwa, Hirokazu Hara, Jun Takeda, Yoshinori Itoh, Tetsuo Adachi

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Diabetic Retinopathy and Cardiovascular Disease: A Literature Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
  5. Review
  6. Anti-Inflammatory Effects of GLP-1R Activation in the Retina.International journal of molecular sciences · 2022
    Review
  7. Copper in the tumor microenvironment and tumor metastasis.Journal of clinical biochemistry and nutrition · 2022
    Article
  8. Review
  9. The Role of Histone Protein Acetylation in Regulating Endothelial Function.Frontiers in cell and developmental biology · 2021
    Review
  10. Targeting epigenetic mechanisms in diabetic wound healing.Translational research : the journal of laboratory and clinical medicine · 2019
    Review
  11. Review
  12. Extracellular superoxide dismutase and its role in cancer.Free radical biology & medicine · 2017
    Review
  13. Article
  14. Article
  15. Tumor necrosis factor-α decreases EC-SOD expression through DNA methylation.Journal of clinical biochemistry and nutrition · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hiroyuki YasudaLaboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Atsuko OhashiLaboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Shohei NishidaDepartment of Pharmacy, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194, Japan.
Tetsuro KamiyaLaboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Tetsuya SuwaDepartment of Diabetes and Endocrinology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Hirokazu HaraLaboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Jun TakedaDepartment of Diabetes and Endocrinology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Yoshinori ItohDepartment of Pharmacy, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194, Japan.
Tetsuo AdachiLaboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Gifu Pharmaceutical University · JPGifu University · JPGifu University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular-superoxide dismutase (genetic name

Indexed as

diabetic retinopathyepigeneticsexendin-4extracellular-superoxide dismutaseincretin-based therapy

Identifiers

PMID27895384
PMCPMC5110938
OpenAlexW2513624345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.