ArticleStroke2016
Optimal Computed Tomographic Perfusion Scan Duration for Assessment of Acute Stroke Lesion Volumes.
Article in Stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Predictors of Mortality in Posterior Circulation Ischemic Stroke.Medicina (Kaunas, Lithuania) · 2026Article
- International survey in four European countries on diagnostic reference levels based on clinical indications in computed tomography.Insights into imaging · 2026Article
- Accounting for Truncation Artifacts in Angiographic Perfusion.Translational stroke research · 2026Article
- Article
- Diagnostically competitive performance of a physiology-informed generative multi-task network for contrast-free CT perfusion.Frontiers in human neuroscience · 2026Article
- Contrast bolus timing in CT-angiography and CT-perfusion: insights from a large clinical dataset.Neuroradiology · 2025Article
- Deep learning-based correction for time truncation in cerebral computed tomography perfusion.Radiological physics and technology · 2024Article
- Artificial intelligence software for assessing brain ischemic penumbra/core infarction on computed tomography perfusion: A real-world accuracy study.World journal of radiology · 2024Article
- Impact of temporal resolution on perfusion metrics, therapy decision, and radiation dose reduction in brain CT perfusion in patients with suspected stroke.Neuroradiology · 2024Article
- Detecting CTP truncation artifacts in acute stroke imaging from the arterial input and the vascular output functions.PloS one · 2023Article
- Reduction in Radiation Exposure of CT Perfusion by Optimized Imaging Timing Using Temporal Information of the Preceding CT Angiography of the Carotid Artery in the Stroke Protocol.Diagnostics (Basel, Switzerland) · 2022Article
- CTP: Time for Patient-Tailored Acquisition Protocols.AJNR. American journal of neuroradiology · 2022Article
- Use of CTA Test Dose to Trigger a Low Cardiac Output Protocol Improves Acute Stroke CTP Data Analyzed with RAPID Software.AJNR. American journal of neuroradiology · 2022Article
- Diagnostic Performance of Computed Tomography Angiography and Computed Tomography Perfusion Tissue Time-to-Maximum in Vasospasm Following Aneurysmal Subarachnoid Hemorrhage.Journal of the American Heart Association · 2022Article
- Review
- Normative distribution of posterior circulation tissue time-to-maximum: Effects of anatomic variation, tracer kinetics, and implications for patient selection in posterior circulation ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- A dynamic simulation framework for CT perfusion in stroke assessment built from first principles.Medical physics · 2021Article
- CT perfusion in acute stroke: Practical guidance for implementation in clinical practice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
background and purposeThe minimal scan duration needed to obtain reliable lesion volumes with computed tomographic perfusion (CTP) has not been well established in the literature.
methodsWe retrospectively assessed the impact of gradual truncation of the scan duration on acute ischemic lesion volume measurements. For each scan, we identified its optimal scan time, defined as the shortest scan duration that yields measurements of the ischemic lesion volumes similar to those obtained with longer scanning, and the relative height of the fitted venous output function at its optimal scan time.
resultsWe analyzed 70 computed tomographic perfusion scans of acute stroke patients. An optimal scan time could not be determined in 11 scans (16%). For the other 59 scans, the median optimal scan time was 32.7 seconds (90th percentile 52.6 seconds; 100th percentile 68.9 seconds), and the median relative height of the fitted venous output function at the optimal scan times was 0.39 (90th percentile 0.02; 100th percentile 0.00). On the basis of a linear model, the optimal scan time was T
conclusionsThis study shows how the optimal duration of a computed tomographic perfusion scan relates to the arrival time and width of the contrast bolus. This knowledge can be used to optimize computed tomographic perfusion scan protocols and to determine whether a scan is of sufficient duration. Provided a baseline (T
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