ArticleThe American journal of tropical medicine and hygiene2017
Results from the Workshop "Problem Formulation for the Use of Gene Drive in Mosquitoes".
Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- A typology of community and stakeholder engagement based on documented examples in the field of novel vector control.PLoS neglected tropical diseases · 2019Pooled it
- Post-release monitoring pathway for the deployment of gene drive-modified mosquitoes for malaria control in Africa.Malaria journal · 2024Article
- Practical Application of a Relationship-Based Model to Engagement for Gene-Drive Vector Control Programs.The American journal of tropical medicine and hygiene · 2024Article
- Advances and challenges in synthetic biology for mosquito control.Trends in parasitology · 2024Review
- Conceptual risk assessment of mosquito population modification gene-drive systems to control malaria transmission: preliminary hazards list workshops.Frontiers in bioengineering and biotechnology · 2023Article
- Larval mosquito management and risk to aquatic ecosystems: A comparative approach including current tactics and gene-drive Anopheles techniques.Transgenic research · 2022Article
- Lessons learned from the introduction of genetically engineered crops: relevance to gene drive deployment in Africa.Transgenic research · 2022Review
- Ethical Considerations for Gene Drive: Challenges of Balancing Inclusion, Power and Perspectives.Frontiers in bioengineering and biotechnology · 2022Article
- Gene drive strategies of pest control in agricultural systems: Challenges and opportunities.Evolutionary applications · 2021Article
- Article
- Experts' moral views on gene drive technologies: a qualitative interview study.BMC medical ethics · 2021Article
- Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post-market environmental monitoring of genetically modified insects containing engineered gene drives.EFSA journal. European Food Safety Authority · 2020Article
- Article
- Next-generation gene drive for population modification of the malaria vector mosquito,Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Toward the Definition of Efficacy and Safety Criteria for Advancing Gene Drive-Modified Mosquitoes to Field Testing.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2020Review
- Public health concerns over gene-drive mosquitoes: will future use of gene-drive snails for schistosomiasis control gain increased level of community acceptance?Pathogens and global health · 2020Review
- Providing a policy framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research.Wellcome open research · 2020Article
- Problem formulation for gene drive mosquitoes designed to reduce malaria transmission in Africa: results from four regional consultations 2016-2018.Malaria journal · 2019Article
- Informed consent and community engagement in open field research: lessons for gene drive science.BMC medical ethics · 2019Article
- Using problem formulation for fit-for-purpose pre-market environmental risk assessments of regulated stressors.EFSA journal. European Food Safety Authority · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reducing the incidence of malaria has been a public health priority for nearly a century. New technologies and associated vector control strategies play an important role in the prospect of sustained reductions. The development of the CRISPR/Cas9 gene editing system has generated new possibilities for the use of gene-drive constructs to reduce or alter vector populations to reduce malaria incidence. However, before these technologies can be developed and exploited, it will be necessary to understand and assess the likelihood of any potential harms to humans or the environment. To begin this process, the Foundation for the National Institutes of Health and the International Life Sciences Institute Research Foundation organized an expert workshop to consider the potential risks related to the use of gene drives in
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.