Evidence map›Paper›PMID 27895202›Full record

ArticlePlant physiology2017

The LBD12-1 Transcription Factor Suppresses Apical Meristem Size by Repressing Argonaute 10 Expression.

Weiwei Ma, Fuqing Wu, Peike Sheng, Xiaole Wang, Zhe Zhang, Kunneng Zhou, Huan Zhang, Jinlong Hu, Qibin Lin, Zhijun Cheng and 8 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  4. The LBD Transcription FactorPlants (Basel, Switzerland) · 2025
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  11. Article
  12. Article
  13. Article
  14. Article
  15. Plants (Basel, Switzerland) · 2022
    Article
  16. Molecular Determinants ofFrontiers in plant science · 2022
    Review
  17. Article
  18. Article
  19. Phylogeny and Functions of LOB Domain Proteins in Plants.International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Weiwei MaNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Fuqing WuNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0002-4172-3868
Peike ShengNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Xiaole WangNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Zhe ZhangNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Kunneng ZhouNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Huan ZhangNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0002-0257-0248
Jinlong HuNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Qibin LinNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Zhijun ChengNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0002-2768-8162
Jiulin WangNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0003-4375-4892
Shanshan ZhuNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Xin ZhangNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0002-2519-4441
Xiuping GuoNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0002-4936-7562
Haiyang WangNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.ORCID 0000-0002-1302-5747
Chuanyin WuNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Huqu ZhaiNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and.
Jianmin WanNational Key Facility for Crop Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China (W.M., F.W., P.S., X.W., Z.Z., Q.L., Z.C., J. Wang, S.Z., X.Z., X.G., H.W., C.W., H.Z., J. Wan); and wanjianmin@caas.cn.ORCID 0000-0002-7813-4362
Nanjing Agricultural University · CNChinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The shoot apical meristem (SAM) consists of a population of multipotent cells that generates all aerial structures and regenerates itself. SAM maintenance and lateral organ development are regulated by several complex signaling pathways, in which the Argonaute gene-mediated pathway plays a key role. One Argonaute gene, AGO10, functions as a microRNA locker that attenuates miR165/166 activity and positively regulates shoot apical meristem development, but little is known about when and how AGO10 is regulated at the transcriptional level. In this work, we showed that transgenic rice plants overexpressing LBD12-1, an LBD family transcription factor, exhibited stunted growth, twisted leaves, abnormal anthers, and reduced SAM size. Further research revealed that LBD12-1 directly binds to the promoter region and represses the expression of AGO10. Overexpression of AGO10 in an LBD12-1 overexpression background rescued the growth defect phenotype of LBD12-1-overexpressing plants. The expression of LBD12-1 and its binding ability to the AGO10 promoter is induced by stress. lbd12-1 loss-of-function mutants showed similar phenotypes and SAM size to the wild type under normal conditions, but lbd12-1 had a larger SAM under salt stress. Our findings provide novel insights into the regulatory mechanism of AGO10 by which SAM size is controlled under stress conditions.

Indexed as

ArabidopsisArabidopsis ProteinsArgonaute ProteinsGene Expression Regulation, PlantMeristemNicotianaPhylogenyPlants, Genetically ModifiedPromoter Regions, GeneticRepressor ProteinsStress, PhysiologicalTranscription FactorsArabidopsis ProteinsArgonaute ProteinsAT5G43810 protein, ArabidopsisRepressor ProteinsTranscription Factors

Identifiers

PMID27895202
PMCPMC5210715
OpenAlexW2558018199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.