Evidence map›Paper›PMID 27895167›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

PGI2 Controls Pulmonary NK Cells That Prevent Airway Sensitization to House Dust Mite Allergen.

Bryan Simons, Maria E Ferrini, Sophia Carvalho, David J P Bassett, Zeina Jaffar, Kevan Roberts

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Unconventional functions of natural killer cells in homeostasis and disease.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Review
  2. Review
  3. Review
  4. Natural killer cells in the lung: potential role in asthma and virus-induced exacerbation?European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Innate-like Lymphocytes and Innate Lymphoid Cells in Asthma.Clinical reviews in allergy & immunology · 2020
    Review
  10. Review
  11. Article
  12. T cells in severe childhood asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019
    Review
  13. Role of Natural Killer Cells in Airway Inflammation.Allergy, asthma & immunology research · 2018
    Review
  14. Role of NKp46EMBO molecular medicine · 2018
    Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bryan SimonsCenter for Environmental Health Sciences, Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT 59812; and.
Maria E FerriniCenter for Environmental Health Sciences, Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT 59812; and.
Sophia CarvalhoCenter for Environmental Health Sciences, Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT 59812; and.
David J P BassettDepartment of Family Medicine and Public Health Sciences, School of Medicine, Wayne State University, Detroit, MI 48201.
Zeina JaffarCenter for Environmental Health Sciences, Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT 59812; and kevan.roberts@umontana.edu zeina.jaffar@umontana.edu.
Kevan RobertsCenter for Environmental Health Sciences, Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT 59812; and kevan.roberts@umontana.edu zeina.jaffar@umontana.edu.
Center for Environmental Health · USUniversity of Montana · USWayne State University · US

Funding

Molecular Histology and Fluorescent ImagingP30GM103338 · NIGMS · UNIVERSITY OF MONTANA · PI HOLIAN, ANDRIJ · 2013 to 2017
$5.6M
MECHANISMS THAT REGULATE TH2-MEDIATED LUNG INFLAMMATIONR01HL079189 · NHLBI · UNIVERSITY OF MONTANA · PI ROBERTS, KEVAN · 2005 to 2009
$1.7M
Prevention of airway sensitization to airborne house dust mite allergenR15HL135696 · NHLBI · UNIVERSITY OF MONTANA · PI ROBERTS, KEVAN · 2017 to 2017
$432k
CB2 agonists as novel therapeutic agents that limit allergic lung inflammationR15HL112073 · NHLBI · UNIVERSITY OF MONTANA · PI JAFFAR, ZEINA · 2012 to 2012
$410k
Upgrade of current CompuCyte LSC??? to the CompuCyte iCys??? Laser Scanning CytomS10RR026325 · NCRR · UNIVERSITY OF MONTANA · PI ROBERTS, KEVAN · 2010 to 2010
$306k
NCRR NIH HHS S10 RR026325NHLBI NIH HHS R01 HL079189NHLBI NIH HHS R15 HL112073NHLBI NIH HHS R15 HL135696NIGMS NIH HHS P30 GM103338
6 · The paper itself

Abstract

In allergic asthma, inhalation of airborne allergens such as the house dust mite (HDM) effectively activates both innate and adaptive immunity in the lung mucosa. To determine the role of the eicosanoid PGI

Indexed as

AnimalsAntigens, DermatophagoidesDisease Models, AnimalEpoprostenolFlow CytometryImmunohistochemistryKiller Cells, NaturalLungMiceMice, Inbred C57BLMice, KnockoutPyroglyphidaeReceptors, EpoprostenolRespiratory HypersensitivityAntigens, DermatophagoidesEpoprostenolReceptors, Epoprostenol

Identifiers

PMID27895167
PMCPMC5173397
OpenAlexW2559169834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.