Evidence map›Paper›PMID 27895105›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Robot-assisted mechanical therapy attenuates stroke-induced limb skeletal muscle injury.

Chandan K Sen, Savita Khanna, Hallie Harris, Richard Stewart, Maria Balch, Mallory Heigel, Seth Teplitsky, Surya Gnyawali, Cameron Rink

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Wireless Magnetic Robot for Precise Hierarchical Control of Tissue Deformation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Molecular mechanism of cerebral edema improvement via IL-1RA released from the stroke-unaffected hindlimb by treadmill exercise after cerebral infarction in rats.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  5. Article
  6. Article
  7. Quantifiable Soft Tissue Manipulation (QSTM™) - A novel modality to improve clinical manual therapy with objective metrics.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Phytoestrogen isoflavone intervention to engage the neuroprotective effect of glutamate oxaloacetate transaminase against stroke.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chandan K SenDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Savita KhannaDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Hallie HarrisDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Richard StewartDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Maria BalchDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Mallory HeigelDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Seth TeplitskyDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Surya GnyawaliDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Cameron RinkDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA cameron.rink@osumc.edu.
The Ohio State University Wexner Medical Center · US

Funding

Vitamin E Neuroprotection: Novel Molecular MechanismsR01NS042617 · NINDS · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K · 2002 to 2021
$3.9M
iGOT neuroprotectionR01NS085272 · NINDS · OHIO STATE UNIVERSITY · PI KHANNA, SAVITA, RINK, CAMERON LUCIAN · 2013 to 2017
$1.7M
NINDS NIH HHS R01 NS042617NINDS NIH HHS R01 NS085272
6 · The paper itself

Abstract

The efficacy and optimization of poststroke physical therapy paradigms is challenged in part by a lack of objective tools available to researchers for systematic preclinical testing. This work represents a maiden effort to develop a robot-assisted mechanical therapy (RAMT) device to objectively address the significance of mechanical physiotherapy on poststroke outcomes. Wistar rats were subjected to right hemisphere middle-cerebral artery occlusion and reperfusion. After 24 h, rats were split into control (RAMT

Indexed as

AnimalsBrain-Derived Neurotrophic FactorCytokinesHindlimbMaleMuscle, SkeletalMyostatinPhysical Therapy ModalitiesRatsRats, WistarRegional Blood FlowRoboticsStroke RehabilitationBrain-Derived Neurotrophic FactorCytokinesMyostatincerebrovascular accidentischemiaphysical therapyrehabilitation

Identifiers

PMID27895105
PMCPMC5295731
OpenAlexW2557532550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.