Evidence map›Paper›PMID 27895024›Full record

ArticleCirculation2016

The Role of Calcium/Calmodulin-Dependent Protein Kinase II Activation in Hypertrophic Cardiomyopathy.

Jil C Tardiff

Open access · bronzeAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Hypertrophic cardiomyopathy mutations increase myofilament CaThe Journal of biological chemistry · 2018
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jil C TardiffFrom Departments of Internal Medicine and Cellular and Molecular Medicine, University of Arizona, Tucson. jtardiff@email.arizona.edu.
University of Arizona · US

Funding

Integrative Approach to Divergent Remodeling in Thin Filament CardiomyopathiesR01HL075619 · NHLBI · UNIVERSITY OF ARIZONA · PI TARDIFF, JIL C · 2004 to 2025
$8.6M
The interaction of myosin and the thin filament: how mutations cause allosteric dysfunction and their connection to genetic cardiomyopathyR01HL107046 · NHLBI · UNIVERSITY OF ARIZONA · PI SCHWARTZ, STEVEN D, TARDIFF, JIL C · 2011 to 2023
$6.0M
NHLBI NIH HHS R01 HL075619NHLBI NIH HHS R01 HL107046
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiomyopathy, HypertrophicCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium SignalingGenotypeHumansCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2calcium/calmodulin-dependent protein kinase IIcalcium regulationcardiac remodelingEditorialsgeneticshumanhypertrophic cardiomyopathy

Identifiers

PMID27895024
PMCPMC5358792
OpenAlexW2558270198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.