Evidence map›Paper›PMID 27894545›Full record

ArticleAmerican journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics2016

Ability of mini-implant-facilitated micro-osteoperforations to accelerate tooth movement in rats.

Tracy Cheung, Juyoung Park, Deborah Lee, Catherine Kim, Jeffrey Olson, Shadi Javadi, Gregory Lawson, James McCabe, Won Moon, Kang Ting and 1 more

2 registry-linked trialsOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04999150 nacompletednot on this mapstarted 2018, after this paper: background citation

A Split-Mouth Randomized Clinical Trial for the Comparison of Corticotomy and Micro-Osteoperforations During Canine Retraction: A Pilot Study

TypeinterventionalSponsorUniversity of Puerto RicoRan2018 to 2020Enrolled13ConditionsMalocclusion, Class I/IIArmsMicro-Osteoperforations, Corticotomy
NCT05339620 nacompletednot on this mapstarted 2018, after this paper: background citation

Effect of Implant Driver Facilitated Micro-osteo Perforations on the Rate of Tooth Movement.

TypeinterventionalSponsorBahria UniversityRan2018 to 2022Enrolled22ConditionsTooth Movement TechniquesArmsimplant driver facilitated micro-osteoperforations
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 77 citations in OpenAlex.

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  4. Effects of micro-osteoperforations on intraoral miniscrew anchored maxillary molar distalization : A randomized clinical trial.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tracy CheungResident, Section of Orthodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Juyoung ParkGraduate student, Division of Oral Biology, University of California at Los Angeles, Los Angeles, Calif.
Deborah LeeGraduate student, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Catherine KimGraduate student, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Jeffrey OlsonGraduate student, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Shadi JavadiAssistant project scientist, Section of Orthodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Gregory LawsonDirector, Pathology and Laboratory Medicine, Division of Laboratory Animal Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, Calif.
James McCabeTraining manager, Division of Laboratory Animal Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, Calif.
Won MoonClinical associate professor, Section of Orthodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Kang TingChair and professor, Section of Orthodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif.
Christine HongAssistant professor, Section of Orthodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, Calif. Electronic address: chong@dentistry.ucla.edu.
University of California, Los Angeles · US

Funding

Promoting DMSC-mediated craniofacial regeneration by estrogenK08DE024603 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HONG, CHRISTINE · 2014 to 2018
$666k
NIDCR NIH HHS K08 DE024603
6 · The paper itself

Abstract

introductionAlthough current techniques for accelerated tooth movement often involve invasive surgical procedures, micro-osteoperforations (MOPs) using mini-implants may facilitate orthodontic tooth movement without raising flaps, reduce surgical risks, and increase patient acceptance. In this study, we evaluated the effectiveness of mini-implant-facilitated MOPs in inducing accelerated tooth movement and investigated the potential risks for root resorption.

methodsFive MOPs were placed on the left side around the maxillary first molars in 6 rats using an automated mini-implant driver, whereas the right side received no MOPs as the control. Closed-coiled springs were secured from incisors to first molars for orthodontic tooth movement. Tooth movement was measured, and samples underwent radiologic and histologic analyses.

resultsThe MOP side exhibited a 1.86-fold increase in the rate of tooth movement with decreased bone density and bone volume around the first molars compared with the control side. Hematoxylin and eosin and tartrate-resistant acid phosphatase analyses showed increased numbers of osteoclasts as well as new bone formation. Three-dimensional volumetric analysis of all 5 roots of the maxillary first molars demonstrated no statistically significant difference in root volumes.

conclusionsMini-implant-facilitated MOPs accelerated tooth movement without increased risk for root resorption and therefore may become a readily available and efficient treatment option to shorten orthodontic treatment time with improved patient acceptance.

Indexed as

Orthodontic WiresAnimalsMaleMandibleMolarRatsRats, Sprague-DawleyRoot ResorptionTooth Movement TechniquesX-Ray Microtomography

Identifiers

PMID27894545
PMCPMC5131371
OpenAlexW2555383851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.