Evidence map›Paper›PMID 27894494›Full record

ReviewCritical care clinics2017

Optimal Fluid Therapy for Traumatic Hemorrhagic Shock.

Ronald Chang, John B Holcomb

Open access · greenAbstract readReview
In one paragraph

Review in Critical care clinics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

  1. Crystalloid vs colloid fluid resuscitation in polytrauma patients: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  2. Trial
  3. The unrestricted global effort to complete the COOL trial.World journal of emergency surgery : WJES · 2023
    Trial
  4. Trial
  5. Article
  6. Article
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  8. Unstable pelvic fractures in patients with hemodynamic instability: global treatment controversies.OTA international : the open access journal of orthopaedic trauma · 2025
    Article
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  10. Article
  11. Article
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  17. Observational
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ronald ChangCenter for Translational Injury Research, University of Texas Health Science Center, 6410 Fannin Street, Suite 1100, Houston, TX 77030, USA. Electronic address: ronald.chang@uth.tmc.edu.
John B HolcombDepartment of Surgery, University of Texas Health Science Center, 6410 Fannin Street, Suite 1100, Houston, TX 77030, USA.
The University of Texas Health Science Center · US

Funding

ROLE OF THE GUT IN POST INJURY MULTIPLE ORGAN FAILURET32GM008792 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Charles S Cox · 2001 to 2026
$5.2M
NIGMS NIH HHS T32 GM008792
6 · The paper itself

Abstract

The resuscitation of traumatic hemorrhagic shock has undergone a paradigm shift in the last 20 years with the advent of damage control resuscitation (DCR). Major principles of DCR include minimization of crystalloid, permissive hypotension, transfusion of a balanced ratio of blood products, and goal-directed correction of coagulopathy. In particular, plasma has replaced crystalloid as the primary means for volume expansion for traumatic hemorrhagic shock. Predicting which patient will require DCR by prompt and accurate activation of a massive transfusion protocol, however, remains a challenge.

Indexed as

Practice Guidelines as TopicBlood TransfusionFluid TherapyHumansIsotonic SolutionsResuscitationShock, HemorrhagicIsotonic SolutionsDamage control resuscitationHemorrhagic shockMassive transfusion protocol

Identifiers

PMID27894494
PMCPMC5131713
OpenAlexW2555737727

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.