Evidence map›Paper›PMID 27894492›Full record

ReviewCritical care clinics2017

Management of Trauma-Induced Coagulopathy with Thrombelastography.

Eduardo Gonzalez, Ernest E Moore, Hunter B Moore

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Critical care clinics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03380767 (Use of Viscoelastic Tests in the Treatment of Trauma-induced Coagulopathy), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03380767 nawithdrawnnot on this mapstarted 2019, after this paper: background citation

Use of Viscoelastic Tests in the Treatment of Trauma-induced Coagulopathy: a Pragmatic Randomized Clinical Trial Comparing Viscoelastic Tests With Conventional Assays.

TypeinterventionalSponsorA.O. Ospedale Papa Giovanni XXIIIRan2019 to 2021Enrolled0ConditionsTrauma, Multiple, Coagulopathy, Massive HemorrhageArmsTrauma-induced coagulopathy treatment
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Coagulation Factor XIII - Last to think about?Blood transfusion = Trasfusione del sangue · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Toxins · 2023
    Article
  16. Review
  17. Measurement of Blood Viscoelasticity Using Thromboelastography.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eduardo GonzalezDepartment of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA.
Ernest E MooreDepartment of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA; Department of Surgery, Denver Health Medical Center, 77 Bannock Street, Denver, CO 80204, USA; Editorial office, Journal of Trauma and Acute Care Surgery, 655 Broadway, Suite 365, Denver, CO 80203, USA. Electronic address: ernest.moore@dhha.org.
Hunter B MooreDepartment of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA.
University of Colorado Denver · USDenver Health Medical Center · US

Funding

Analysis and Characterization of Trauma-Induced CoagulopathyUM1HL120877 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI MORRISSEY, JAMES H., WISNIEWSKI, STEPHEN R · 2013 to 2019
$26.6M
Trauma Reprograms CellsP50GM049222 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI BANERJEE, ANIRBAN · 1993 to 2017
$26.1M
Mechanisms of Trauma-Induced CoagulopathyT32GM008315 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Mitchell Cohen, ELIZABETH J. KOVACS · 1991 to 2026
$7.1M
NHLBI NIH HHS UM1 HL120877NIGMS NIH HHS P50 GM049222NIGMS NIH HHS T32 GM008315
6 · The paper itself

Abstract

Viscoelastic assays, such as thrombelastography (TEG) and rotational thrombelastometry (ROTEM), have emerged as point-of-care tools that can guide the hemostatic resuscitation of bleeding injured patients. This article describes the role of TEG in contemporary trauma care by explaining this assay's methodology, clinical applications, and result interpretation through description of supporting studies to provide the reader with an evidence-based user's guide. Although TEG and ROTEM are assays based on the same viscoelastic principle, this article is focused on data supporting the use of TEG in trauma, because it is available in trauma centers in North America; ROTEM is mostly available in Europe.

Indexed as

Practice Guidelines as TopicBlood Coagulation DisordersEuropeHumansNorth AmericaThrombelastographyWounds and InjuriesCoagulopathyFibrinolysisResuscitationTEGThrombelastographyTransfusion

Identifiers

PMID27894492
PMCPMC5142763
OpenAlexW2555777785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.