Evidence map›Paper›PMID 27894353›Full record

Observational studyMalaria journal2016

Provider and user acceptability of intermittent screening and treatment for the control of malaria in pregnancy in Malawi.

Deborah Almond, Mwayi Madanitsa, Victor Mwapasa, Linda Kalilani-Phiri, Jayne Webster, Feiko Ter Kuile, Lucy Paintain

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Deborah AlmondDisease Control Department, London School of Hygiene and Tropical Medicine, London, UK.
Mwayi MadanitsaCollege of Medicine, University of Malawi, Blantyre, Malawi.
Victor MwapasaCollege of Medicine, University of Malawi, Blantyre, Malawi.
Linda Kalilani-PhiriCollege of Medicine, University of Malawi, Blantyre, Malawi.
Jayne WebsterDisease Control Department, London School of Hygiene and Tropical Medicine, London, UK.
Feiko Ter KuileDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Lucy PaintainDisease Control Department, London School of Hygiene and Tropical Medicine, London, UK. Lucy.Paintain@lshtm.ac.uk.ORCID http://orcid.org/0000-0003-0689-0473
University of Malawi · MWLondon School of Hygiene & Tropical Medicine · GBLiverpool School of Tropical Medicine · GBUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria in pregnancy is a major cause of adverse maternal and fetal outcomes. Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) is one of the control strategies promoted by WHO. In response to mounting resistance to SP, intermittent screening and treatment (ISTp) has been proposed as an alternative. The objective of this study was to explore the acceptability of ISTp for health workers and pregnant women.

methodsSemi-structured interviews of ten health workers and five focus group discussions of 38 women enrolled in an ongoing trial comparing IPTp-SP and ISTp with dihydroartemisinin-piperaquine (DP) were conducted at two antenatal clinics in rural Malawi. All transcripts were coded and themes were identified using a content analysis approach.

resultsAmongst health workers, there were contrasting opinions on the preference of blood sampling methods, and the influence of method on reliability of diagnosis. The perceived greater effectiveness of DP compared to SP was appreciated, however concerns of user compliance with the full dose of DP in non-trial settings were raised. Despite the discomfort of repeated finger pricks, pregnant women were generally accepting of ISTp, particularly the chance for regular blood tests to check for infections and the perceived greater effectiveness with fewer side effects of DP compared to SP.

conclusionIn the trial context, pregnant women tended to prefer ISTp-DP over IPTp-SP. Health workers were also accepting of ISTp-DP as an alternative to IPTp-SP in light of increasing SP resistance. However, reliability of stock, adherence to malaria test results and user adherence to the full course of DP may present barriers to successful routine implementation. Effective communication with health workers and between health workers, pregnant women and their communities will be essential for the acceptability of focused antenatal care, including the best malaria control measures available.

Indexed as

Health PersonnelPatient Acceptance of Health CarePregnant PeopleAdolescentAdultAntimalarialsFemaleHumansInfant, NewbornInterviews as TopicMalariaMalawiMass ScreeningPregnancyPregnancy Complications, InfectiousYoung AdultAntimalarialsAcceptabilityIntermittent screening and treatmentMalaria in pregnancy

Identifiers

PMID27894353
PMCPMC5126811
OpenAlexW2559485779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.