Trial reportBehaviour research and therapy2017
A non-inferiority trial of Prolonged Exposure for posttraumatic stress disorder: In person versus home-based telehealth.
Trial report in Behaviour research and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness and moderators of PE and CPT in adult PTSD treatment: a systematic review and meta-analysis.European journal of psychotraumatology · 2026Pooled it
- Effectiveness of Videoconference-Delivered Cognitive Behavioral Therapy for Adults With Psychiatric Disorders: Systematic and Meta-Analytic Review.Journal of medical Internet research · 2021Pooled it
- Implementation of Telemental Health Services Before COVID-19: Rapid Umbrella Review of Systematic Reviews.Journal of medical Internet research · 2021Pooled it
- A Systematic Review of the Evidence Supporting Mobile- and Internet-Based Psychological Interventions For Self-Harm.Suicide & life-threatening behavior · 2020Pooled it
- Online-delivered eye movement desensitization and reprocessing treatment for adults with post-traumatic stress disorder due to multiple traumas: a non-concurrent multiple baseline design.European journal of psychotraumatology · 2026Trial
- A novel prolonged exposure therapy protocol for improving therapy session attendance and PTSD symptoms among adults receiving buprenorphine or methadone treatment.Drug and alcohol dependence · 2025Trial
- Peer support during in vivo exposure homework increases likelihood of prolonged exposure therapy completion.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2025Trial
- Prolonged exposure therapy for PTSD in individuals with opioid use disorder: A randomized pilot study.Addictive behaviors · 2023Trial
- Feasibility and Acceptability of Prolonged Exposure in Primary Care (PE-PC) for Posttraumatic Stress Disorder in Federally Qualified Health Centers: A Pilot Study.Administration and policy in mental health · 2022Trial
- Trial
- Child and parent secondary outcomes in stepped care versus standard care treatment for childhood trauma.Journal of affective disorders · 2022Trial
- Posttraumatic stress disorder in individuals seeking treatment for opioid use disorder in Vermont.Preventive medicine · 2021Trial
- Music therapy was noninferior to verbal standard treatment of traumatized refugees in mental health care: Results from a randomized clinical trial.European journal of psychotraumatology · 2021Trial
- Emotion Dysregulation Predicts Dropout from Prolonged Exposure Treatment among Women Veterans with Military Sexual Trauma-Related Posttraumatic Stress Disorder.Women's health issues : official publication of the Jacobs Institute of Women's HealthTrial
- Rural-Urban and Racial-Ethnic Differences in Tele-Behavioral Health Access for Medicaid Beneficiaries.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026Article
- Telebehavioral Health, In-Person, and Hybrid Modalities of Treatment Delivery Among US Service Members: Longitudinal Observational Study.JMIR mental health · 2026Observational
- EMpower Parents: Effectiveness of EMDR treatment for parental PTSD related to a child's medical condition in a randomized controlled trial.BMC psychology · 2025Article
- Reducing Depression and Suicidal Ideation Among Elder Abuse Victims Using PROTECT.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025Article
- Uses of Virtual Care in Primary Care: Scoping Review.Journal of medical Internet research · 2025Article
- Improved outcomes for depressed elder abuse victims with video-delivered psychotherapy during COVID-19.Psychotherapy research : journal of the Society for Psychotherapy Research · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
This is the first randomized controlled trial to evaluate non-inferiority of Prolonged Exposure (PE) delivered via home-based telehealth (HBT) compared to standard in-person (IP) PE. One-hundred thirty two Veterans recruited from a Southeastern Veterans Affairs Medical Center and affiliated University who met criteria for posttraumatic stress disorder (PTSD) were randomized to receive PE via HBT or PE via IP. Results indicated that PE-HBT was non-inferior to PE-IP in terms of reducing PTSD scores at post-treatment, 3 and 6 month follow-up. However, non-inferiority hypotheses for depression were only supported at 6 month follow-up. HBT has great potential to reduce patient burden associated with receiving treatment in terms of travel time, travel cost, lost work, and stigma without sacrificing efficacy. These findings indicate that telehealth treatment delivered directly into patients' homes may dramatically increase the reach of this evidence-based therapy for PTSD without diminishing effectiveness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.