ArticleeLife2016
Structure of the germline genome of
Open access · goldAbstract read
In one paragraph
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.
0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 168 citations in OpenAlex.
- The mechanistic and evolutionary diversity of programmed DNA elimination.Nature reviews. Genetics · 2026Review
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- Bioinformatic, cell localization, and phylogenetic analyses reveal a novel family of putative lipases in Tetrahymena thermophila.G3 (Bethesda, Md.) · 2026Article
- Transposon targeting non-coding RNA transcription targets G/C-rich tracts and is facilitated by an intrinsically disordered protein in Tetrahymena.Science China. Life sciences · 2026Article
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- Host-transposable element coexistence: a matter of resistance, tolerance and trade-off.The EMBO journal · 2026Review
- The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons.BMC biology · 2026Article
- A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination.Nucleic acids research · 2026Article
- A sequence motif for DNA double-strand break and telomere healing during programmed DNA elimination.bioRxiv : the preprint server for biology · 2026Article
- TERT mRNA peaks during meiotic prophase inmicroPublication biology · 2026Article
- From few to many: How non-model organisms' genomics broadened our understanding of molecular evolution.Genetics and molecular biology · 2026Article
- Soma-derived 30-nt small RNAs are coupled with chromosome breakage and precisely target nontransposon DNA against elimination inScience advances · 2025Article
- Linear covariation between germline and somatic mutation rates across ciliates and mammals.Current biology : CB · 2025Article
- Centromeres drive and take a break.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025Review
- Importin-9 and a TPR domain protein MpH drive periodic patterning of ciliary arrays in Tetrahymena.The Journal of cell biology · 2025Article
- Identification and characterization of the de novo methyltransferases for eukaryoticScience advances · 2025Article
- A specialized TFIIB is required for transcription of transposon-targeting noncoding RNAs.Nucleic acids research · 2025Article
- Genomic Signatures of Adaptation to Stress Reveal Shared Evolutionary Trends Between Tetrahymena utriculariae and Its Algal Endosymbiont, Micractinium tetrahymenae.Molecular biology and evolution · 2025Article
- Comprehensive genome annotation of the model ciliate Tetrahymena thermophila by in-depth epigenetic and transcriptomic profiling.Nucleic acids research · 2025Article
- Environment-dependent mutualism-parasitism transitions in the incipient symbiosis between Tetrahymena utriculariae and Micractinium tetrahymenae.The ISME journal · 2025Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
36 authors at 10 institutions in 5 countries.
Eileen P HamiltonDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.
Aurélie KapustaDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, United States.ORCID 0000-0002-4131-903X
Piroska E HuvosBiochemistry and Molecular Biology, Southern Illinois University, Carbondale, United States.
Shelby L BidwellJ. Craig Venter Institute, Rockville, United States.
Nikhat ZafarJ. Craig Venter Institute, Rockville, United States.
Haibao TangJ. Craig Venter Institute, Rockville, United States.
Michalis HadjithomasJ. Craig Venter Institute, Rockville, United States.
Vivek KrishnakumarJ. Craig Venter Institute, Rockville, United States.ORCID 0000-0002-5227-0200
Jonathan H BadgerJ. Craig Venter Institute, Rockville, United States.
Elisabet V CalerJ. Craig Venter Institute, Rockville, United States.
Carsten RussEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Qiandong ZengEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Lin FanEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Joshua Z LevinEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Terrance SheaEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Sarah K YoungEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Ryan HegartyEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Riza DazaEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Sharvari GujjaEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Jennifer R WortmanEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Bruce W BirrenEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Chad NusbaumEli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States.
Jainy ThomasDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, United States.
Clayton M CareyDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, United States.
Ellen J PrithamDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, United States.
Cédric FeschotteDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, United States.
Tomoko NotoInstitute of Molecular Biotechnology, Vienna, Austria.
Kazufumi MochizukiInstitute of Molecular Biotechnology, Vienna, Austria.ORCID 0000-0001-7987-9852
Romeo PapazyanDepartment of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, United States.
Sean D TavernaDepartment of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, United States.
Paul H DearMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Donna M Cassidy-HanleyDepartment of Microbiology and Immunology, Cornell University, Ithaca, United States.
Jie XiongInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Wei MiaoInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Eduardo OriasDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.
Robert S CoyneJ. Craig Venter Institute, Rockville, United States.ORCID 0000-0002-7693-3996
Broad Institute · USJ. Craig Venter Institute · USUniversity of Utah · USChinese Academy of Sciences · CNInstitute of Molecular Biotechnology · ATJohns Hopkins University · USUniversity of California, Santa Barbara · USCornell University · USMRC Laboratory of Molecular Biology · GBSouthern Illinois University Carbondale · US
Funding
Large Scale Sequencing and Analysis of GenomesU54HG003067 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GABRIEL, STACEY, LANDER, ERIC S · 2004 to 2015
$568.6MHuman DNA transposons: evolutionary history and genomic impactR01GM077582 · NIGMS · UNIVERSITY OF UTAH · PI FESCHOTTE, CEDRIC · 2007 to 2015
$1.4MMedical Research Council MC_U105178788NHGRI NIH HHS U54 HG003067NIGMS NIH HHS R01 GM077582
Abstract
The germline genome of the binucleated ciliate
Indexed as
Gene RearrangementGenome, ProtozoanSequence Analysis, DNATetrahymena thermophilacentromerechromosome breakagechromosomesevolutionary biologygenesgenome rearrangementgenomicsintermal eliminated sequenceTetrahymena thermophilatransposable element
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.